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An implantable MOSFET dosimeter for the measurement of radiation dose in tissue during cancer therapy

Publication ,  Journal Article
Beyer, GP; Mann, GG; Pursley, JA; Espenhahn, ET; Fraisse, C; Godfrey, DJ; Oldham, M; Carrea, TB; Bolick, N; Scarantino, CW
Published in: IEEE Sensors Journal
January 1, 2008

This paper describes the functionality, radiation characteristics, and clinical implementation of an implantable MOSFET radiation detector (dosimeter). The dosimeter is powered by radio frequency telemetry eliminating the need for a power source inside the dosimeter. The data can be accessed telemetrically for each treatment day during the course of therapy. The detector has been validated in vitro to confirm its accuracy. Variance between predicted and measured dose in patients is discussed. Factors such as patient setup, treatment plan error, and physiologic motion can affect the accuracy of dose delivery in moving from in vitro to in vivo dose measurements. The initial data suggests that the dosimeters can play a useful role in tracking dose discrepancies, both random and systematic, in patients treated with external beam radiation therapy. The implantable dosimeter can be used, together with the current radiation delivery and planning techniques, to optimize radiation treatment on an individual basis. © 2007 IEEE.

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Published In

IEEE Sensors Journal

DOI

ISSN

1530-437X

Publication Date

January 1, 2008

Volume

8

Issue

1

Start / End Page

38 / 51

Related Subject Headings

  • Analytical Chemistry
  • 40 Engineering
  • 0913 Mechanical Engineering
  • 0906 Electrical and Electronic Engineering
  • 0205 Optical Physics
 

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Beyer, G. P., Mann, G. G., Pursley, J. A., Espenhahn, E. T., Fraisse, C., Godfrey, D. J., … Scarantino, C. W. (2008). An implantable MOSFET dosimeter for the measurement of radiation dose in tissue during cancer therapy. IEEE Sensors Journal, 8(1), 38–51. https://doi.org/10.1109/JSEN.2007.912542
Beyer, G. P., G. G. Mann, J. A. Pursley, E. T. Espenhahn, C. Fraisse, D. J. Godfrey, M. Oldham, T. B. Carrea, N. Bolick, and C. W. Scarantino. “An implantable MOSFET dosimeter for the measurement of radiation dose in tissue during cancer therapy.” IEEE Sensors Journal 8, no. 1 (January 1, 2008): 38–51. https://doi.org/10.1109/JSEN.2007.912542.
Beyer GP, Mann GG, Pursley JA, Espenhahn ET, Fraisse C, Godfrey DJ, et al. An implantable MOSFET dosimeter for the measurement of radiation dose in tissue during cancer therapy. IEEE Sensors Journal. 2008 Jan 1;8(1):38–51.
Beyer, G. P., et al. “An implantable MOSFET dosimeter for the measurement of radiation dose in tissue during cancer therapy.” IEEE Sensors Journal, vol. 8, no. 1, Jan. 2008, pp. 38–51. Scopus, doi:10.1109/JSEN.2007.912542.
Beyer GP, Mann GG, Pursley JA, Espenhahn ET, Fraisse C, Godfrey DJ, Oldham M, Carrea TB, Bolick N, Scarantino CW. An implantable MOSFET dosimeter for the measurement of radiation dose in tissue during cancer therapy. IEEE Sensors Journal. 2008 Jan 1;8(1):38–51.

Published In

IEEE Sensors Journal

DOI

ISSN

1530-437X

Publication Date

January 1, 2008

Volume

8

Issue

1

Start / End Page

38 / 51

Related Subject Headings

  • Analytical Chemistry
  • 40 Engineering
  • 0913 Mechanical Engineering
  • 0906 Electrical and Electronic Engineering
  • 0205 Optical Physics