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Update on hemostasis: neurosurgery.

Publication ,  Journal Article
Gerald, AG
Published in: Surgery
October 2007

Achieving and maintaining hemostasis in neurosurgical procedures is critical to the outcome. After trauma to the brain, a cascade of events initiated by tissue factor (TF) or thromboplastin results in a coagulation process that develops into an exaggerated fibrinolytic response, called disseminated intravascular coagulation (DIC). After a discussion of DIC, intraoperative adjuncts used to control bleeding, such as the gelatin sponge, thrombin, microcrystalline collagen, aprotinin, and fibrin sealants, are reviewed. Recombinant factor VIIa (rFVIIa) also is discussed, including its mechanism of action and use in neurosurgery. The ultra-early administration of rFVIIa also is covered, in both the military and the civilian settings.

Duke Scholars

Published In

Surgery

DOI

ISSN

0039-6060

Publication Date

October 2007

Volume

142

Issue

4 Suppl

Start / End Page

S55 / S60

Location

United States

Related Subject Headings

  • Surgery
  • Neurosurgical Procedures
  • Military Medicine
  • Humans
  • Hemostatics
  • Hemostasis
  • Blood Loss, Surgical
  • 3202 Clinical sciences
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Gerald, A. G. (2007). Update on hemostasis: neurosurgery. Surgery, 142(4 Suppl), S55–S60. https://doi.org/10.1016/j.surg.2007.06.030
Gerald, A Grant. “Update on hemostasis: neurosurgery.Surgery 142, no. 4 Suppl (October 2007): S55–60. https://doi.org/10.1016/j.surg.2007.06.030.
Gerald AG. Update on hemostasis: neurosurgery. Surgery. 2007 Oct;142(4 Suppl):S55–60.
Gerald, A. Grant. “Update on hemostasis: neurosurgery.Surgery, vol. 142, no. 4 Suppl, Oct. 2007, pp. S55–60. Pubmed, doi:10.1016/j.surg.2007.06.030.
Gerald AG. Update on hemostasis: neurosurgery. Surgery. 2007 Oct;142(4 Suppl):S55–S60.
Journal cover image

Published In

Surgery

DOI

ISSN

0039-6060

Publication Date

October 2007

Volume

142

Issue

4 Suppl

Start / End Page

S55 / S60

Location

United States

Related Subject Headings

  • Surgery
  • Neurosurgical Procedures
  • Military Medicine
  • Humans
  • Hemostatics
  • Hemostasis
  • Blood Loss, Surgical
  • 3202 Clinical sciences
  • 1103 Clinical Sciences