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Immunopathological and clinical studies in herpes gestationis.

Publication ,  Journal Article
Foidart, JM; Yaar, M; Hall, R; Gaspard, U; Katz, SI
Published in: Br J Obstet Gynaecol
February 1981

Herpes gestationis is a recurring pruritic, vesiculobullous disease of pregnancy and puerperium. Recently, Lawley et al (1979) reported a high frequency (38 per cent) of fetal morbidity and mortality in 40 cases of immunologically proven herpes gestationis. This study was undertaken to determine whether the antibody to skin basement membrane (found in most patients with herpes gestationis) is able to bind to the placenta basement membranes and thereby to threaten the pregnancy. We were unable to detect this antibody in the placental basement membranes of a patient with herpes gestationis, nor could we demonstrate that the anti-basement membrane antibody, found in the sera of herpes gestationis patients, binds to homologous or autologous placentas and fetal membranes. The importance of an accurate diagnosis and appropriate treatment of this condition is discussed.

Duke Scholars

Published In

Br J Obstet Gynaecol

DOI

ISSN

0306-5456

Publication Date

February 1981

Volume

88

Issue

2

Start / End Page

153 / 159

Location

England

Related Subject Headings

  • Skin Diseases, Vesiculobullous
  • Pregnancy Complications
  • Pregnancy
  • Placenta
  • Pemphigoid Gestationis
  • Obstetrics & Reproductive Medicine
  • Immunoglobulin G
  • Humans
  • Female
  • Extraembryonic Membranes
 

Citation

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Foidart, J. M., Yaar, M., Hall, R., Gaspard, U., & Katz, S. I. (1981). Immunopathological and clinical studies in herpes gestationis. Br J Obstet Gynaecol, 88(2), 153–159. https://doi.org/10.1111/j.1471-0528.1981.tb00961.x
Foidart, J. M., M. Yaar, R. Hall, U. Gaspard, and S. I. Katz. “Immunopathological and clinical studies in herpes gestationis.Br J Obstet Gynaecol 88, no. 2 (February 1981): 153–59. https://doi.org/10.1111/j.1471-0528.1981.tb00961.x.
Foidart JM, Yaar M, Hall R, Gaspard U, Katz SI. Immunopathological and clinical studies in herpes gestationis. Br J Obstet Gynaecol. 1981 Feb;88(2):153–9.
Foidart, J. M., et al. “Immunopathological and clinical studies in herpes gestationis.Br J Obstet Gynaecol, vol. 88, no. 2, Feb. 1981, pp. 153–59. Pubmed, doi:10.1111/j.1471-0528.1981.tb00961.x.
Foidart JM, Yaar M, Hall R, Gaspard U, Katz SI. Immunopathological and clinical studies in herpes gestationis. Br J Obstet Gynaecol. 1981 Feb;88(2):153–159.

Published In

Br J Obstet Gynaecol

DOI

ISSN

0306-5456

Publication Date

February 1981

Volume

88

Issue

2

Start / End Page

153 / 159

Location

England

Related Subject Headings

  • Skin Diseases, Vesiculobullous
  • Pregnancy Complications
  • Pregnancy
  • Placenta
  • Pemphigoid Gestationis
  • Obstetrics & Reproductive Medicine
  • Immunoglobulin G
  • Humans
  • Female
  • Extraembryonic Membranes