The roles of orphan nuclear receptors in the development and function of the immune system.
Publication
, Journal Article
Dzhagalov, I; Zhang, N; He, Y-W
Published in: Cell Mol Immunol
December 2004
Hormones and their receptors regulate cell growth, differentiation and apoptosis and also play important roles in immune function. Recent studies on the subfamily of the orphan nuclear receptors known as retinoid-acid related orphan receptors (ROR) have shed important insights on the roles of this group of nuclear proteins in the development and function of the immune system. RORalpha regulates inflammatory cytokine production in both innate and adaptive immune system while RORgamma regulates the normal development of T lymphocyte repertoire and secondary lymphoid organs.
Duke Scholars
Published In
Cell Mol Immunol
ISSN
1672-7681
Publication Date
December 2004
Volume
1
Issue
6
Start / End Page
401 / 407
Location
China
Related Subject Headings
- Trans-Activators
- Receptors, Thyroid Hormone
- Receptors, Retinoic Acid
- Receptors, Cytoplasmic and Nuclear
- Nuclear Receptor Subfamily 1, Group F, Member 3
- Nuclear Receptor Subfamily 1, Group F, Member 2
- Nuclear Receptor Subfamily 1, Group F, Member 1
- Immunology
- Immune System
- Humans
Citation
APA
Chicago
ICMJE
MLA
NLM
Dzhagalov, I., Zhang, N., & He, Y.-W. (2004). The roles of orphan nuclear receptors in the development and function of the immune system. Cell Mol Immunol, 1(6), 401–407.
Dzhagalov, Ivan, Nu Zhang, and You-Wen He. “The roles of orphan nuclear receptors in the development and function of the immune system.” Cell Mol Immunol 1, no. 6 (December 2004): 401–7.
Dzhagalov I, Zhang N, He Y-W. The roles of orphan nuclear receptors in the development and function of the immune system. Cell Mol Immunol. 2004 Dec;1(6):401–7.
Dzhagalov, Ivan, et al. “The roles of orphan nuclear receptors in the development and function of the immune system.” Cell Mol Immunol, vol. 1, no. 6, Dec. 2004, pp. 401–07.
Dzhagalov I, Zhang N, He Y-W. The roles of orphan nuclear receptors in the development and function of the immune system. Cell Mol Immunol. 2004 Dec;1(6):401–407.
Published In
Cell Mol Immunol
ISSN
1672-7681
Publication Date
December 2004
Volume
1
Issue
6
Start / End Page
401 / 407
Location
China
Related Subject Headings
- Trans-Activators
- Receptors, Thyroid Hormone
- Receptors, Retinoic Acid
- Receptors, Cytoplasmic and Nuclear
- Nuclear Receptor Subfamily 1, Group F, Member 3
- Nuclear Receptor Subfamily 1, Group F, Member 2
- Nuclear Receptor Subfamily 1, Group F, Member 1
- Immunology
- Immune System
- Humans