Old enzymes, new tricks: sirtuins are NAD(+)-dependent de-acylases.
Publication
, Journal Article
Hirschey, MD
Published in: Cell Metab
December 7, 2011
Seven mammalian sirtuins are nicotinamide adenine dinucleotide (NAD)(+)-dependent deacetylases and are important modulators of energy metabolism and stress resistance. Two new studies by Du et al. (2011) and Peng et al. (2011) identify a new enzymatic activity for SIRT5, expanding the cellular repertoire of posttranslational modifications targeted by the sirtuins.
Duke Scholars
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Published In
Cell Metab
DOI
EISSN
1932-7420
Publication Date
December 7, 2011
Volume
14
Issue
6
Start / End Page
718 / 719
Location
United States
Related Subject Headings
- Endocrinology & Metabolism
- 3205 Medical biochemistry and metabolomics
- 3101 Biochemistry and cell biology
- 1101 Medical Biochemistry and Metabolomics
- 0601 Biochemistry and Cell Biology
Citation
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Chicago
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MLA
NLM
Hirschey, M. D. (2011). Old enzymes, new tricks: sirtuins are NAD(+)-dependent de-acylases. Cell Metab, 14(6), 718–719. https://doi.org/10.1016/j.cmet.2011.10.006
Hirschey, Matthew D. “Old enzymes, new tricks: sirtuins are NAD(+)-dependent de-acylases.” Cell Metab 14, no. 6 (December 7, 2011): 718–19. https://doi.org/10.1016/j.cmet.2011.10.006.
Hirschey MD. Old enzymes, new tricks: sirtuins are NAD(+)-dependent de-acylases. Cell Metab. 2011 Dec 7;14(6):718–9.
Hirschey, Matthew D. “Old enzymes, new tricks: sirtuins are NAD(+)-dependent de-acylases.” Cell Metab, vol. 14, no. 6, Dec. 2011, pp. 718–19. Pubmed, doi:10.1016/j.cmet.2011.10.006.
Hirschey MD. Old enzymes, new tricks: sirtuins are NAD(+)-dependent de-acylases. Cell Metab. 2011 Dec 7;14(6):718–719.
Published In
Cell Metab
DOI
EISSN
1932-7420
Publication Date
December 7, 2011
Volume
14
Issue
6
Start / End Page
718 / 719
Location
United States
Related Subject Headings
- Endocrinology & Metabolism
- 3205 Medical biochemistry and metabolomics
- 3101 Biochemistry and cell biology
- 1101 Medical Biochemistry and Metabolomics
- 0601 Biochemistry and Cell Biology