Current immunotherapeutic strategies in colon cancer.
Publication
, Journal Article
Morse, M; Langer, L; Starodub, A; Hobeika, A; Clay, T; Lyerly, HK
Published in: Surg Oncol Clin N Am
October 2007
Because chemotherapy is standard in the treatment of colorectal cancer, it is important to demonstrate whether immunizations may be given to patients receiving systemic chemotherapy. Although some studies have demonstrated immune responses in patients with metastatic colorectal carcinoma who failed standard chemotherapy, the setting of minimal residual disease may be the preferred setting for cancer vaccines. It may be important to choose antigens that have functions important to the cancer cell. The best adjuvant is not well established and may depend on the type of immune response desired. The immune system is "programmed" to down-regulate immune responses once they have become activated to avoid the development of autoimmune disease.
Duke Scholars
Published In
Surg Oncol Clin N Am
DOI
ISSN
1055-3207
Publication Date
October 2007
Volume
16
Issue
4
Start / End Page
873 / x
Location
United States
Related Subject Headings
- Vaccination
- Rectal Neoplasms
- Oncology & Carcinogenesis
- Immunotherapy
- Humans
- Colorectal Neoplasms
- Colonic Neoplasms
- Cancer Vaccines
- 3211 Oncology and carcinogenesis
- 1112 Oncology and Carcinogenesis
Citation
APA
Chicago
ICMJE
MLA
NLM
Morse, M., Langer, L., Starodub, A., Hobeika, A., Clay, T., & Lyerly, H. K. (2007). Current immunotherapeutic strategies in colon cancer. Surg Oncol Clin N Am, 16(4), 873–x. https://doi.org/10.1016/j.soc.2007.07.005
Morse, Michael, Lee Langer, Alexander Starodub, Amy Hobeika, Timothy Clay, and H Kim Lyerly. “Current immunotherapeutic strategies in colon cancer.” Surg Oncol Clin N Am 16, no. 4 (October 2007): 873–x. https://doi.org/10.1016/j.soc.2007.07.005.
Morse M, Langer L, Starodub A, Hobeika A, Clay T, Lyerly HK. Current immunotherapeutic strategies in colon cancer. Surg Oncol Clin N Am. 2007 Oct;16(4):873–x.
Morse, Michael, et al. “Current immunotherapeutic strategies in colon cancer.” Surg Oncol Clin N Am, vol. 16, no. 4, Oct. 2007, pp. 873–x. Pubmed, doi:10.1016/j.soc.2007.07.005.
Morse M, Langer L, Starodub A, Hobeika A, Clay T, Lyerly HK. Current immunotherapeutic strategies in colon cancer. Surg Oncol Clin N Am. 2007 Oct;16(4):873–x.
Published In
Surg Oncol Clin N Am
DOI
ISSN
1055-3207
Publication Date
October 2007
Volume
16
Issue
4
Start / End Page
873 / x
Location
United States
Related Subject Headings
- Vaccination
- Rectal Neoplasms
- Oncology & Carcinogenesis
- Immunotherapy
- Humans
- Colorectal Neoplasms
- Colonic Neoplasms
- Cancer Vaccines
- 3211 Oncology and carcinogenesis
- 1112 Oncology and Carcinogenesis