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The TGF-β-related signalling system in mouse development

Publication ,  Journal Article
Hogan, BLM
Published in: Seminars in Developmental Biology
January 1, 1995

Secreted polypeptide signalling molecules of the TGF- superfamily play critical roles during mouse development. There are 20 known members of this diverse family in the mouse, including the TGF-s, inhibin/activins, BMPs, GDFs, and nodal. Mutations in genes for some of these ligands have been identified or created by targeted mutagenesis. A complex network of binding proteins, proteases, and receptors is involved in the processing, presentation and biological activity of TGF-β-related ligands. It is likely that variations in these modifying factors will explain how different genetic backgrounds can influence the severity and penetrance of mutant phenotypes. © 1995 Academic Press Ltd.

Duke Scholars

Published In

Seminars in Developmental Biology

DOI

ISSN

1044-5781

Publication Date

January 1, 1995

Volume

6

Issue

4

Start / End Page

257 / 265
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Hogan, B. L. M. (1995). The TGF-β-related signalling system in mouse development. Seminars in Developmental Biology, 6(4), 257–265. https://doi.org/10.1016/S1044-5781(06)80051-4
Hogan, B. L. M. “The TGF-β-related signalling system in mouse development.” Seminars in Developmental Biology 6, no. 4 (January 1, 1995): 257–65. https://doi.org/10.1016/S1044-5781(06)80051-4.
Hogan BLM. The TGF-β-related signalling system in mouse development. Seminars in Developmental Biology. 1995 Jan 1;6(4):257–65.
Hogan, B. L. M. “The TGF-β-related signalling system in mouse development.” Seminars in Developmental Biology, vol. 6, no. 4, Jan. 1995, pp. 257–65. Scopus, doi:10.1016/S1044-5781(06)80051-4.
Hogan BLM. The TGF-β-related signalling system in mouse development. Seminars in Developmental Biology. 1995 Jan 1;6(4):257–265.

Published In

Seminars in Developmental Biology

DOI

ISSN

1044-5781

Publication Date

January 1, 1995

Volume

6

Issue

4

Start / End Page

257 / 265