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Sample size calculation for weighted rank tests comparing survival distributions under cluster randomization: a simulation method.

Publication ,  Journal Article
Jung, S-H
Published in: J Biopharm Stat
2007

We propose a sample size calculation method for rank tests comparing two survival distributions under cluster randomization with possibly variable cluster sizes. Here, sample size refers to number of clusters. Our method is based on simulation procedure generating clustered exponential survival variables whose distribution is specified by the marginal hazard rate and the intracluster correlation coefficient. Sample size is calculated given significance level, power, marginal hazard rates (or median survival times) under the alternative hypothesis, intracluster correlation coefficient, accrual rate, follow-up period, and cluster size distribution.

Duke Scholars

Published In

J Biopharm Stat

DOI

ISSN

1054-3406

Publication Date

2007

Volume

17

Issue

5

Start / End Page

839 / 849

Location

England

Related Subject Headings

  • Survival Analysis
  • Statistics & Probability
  • Sample Size
  • Research Design
  • Random Allocation
  • Humans
  • Computer Simulation
  • Cluster Analysis
  • Child
  • Algorithms
 

Citation

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Chicago
ICMJE
MLA
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Journal cover image

Published In

J Biopharm Stat

DOI

ISSN

1054-3406

Publication Date

2007

Volume

17

Issue

5

Start / End Page

839 / 849

Location

England

Related Subject Headings

  • Survival Analysis
  • Statistics & Probability
  • Sample Size
  • Research Design
  • Random Allocation
  • Humans
  • Computer Simulation
  • Cluster Analysis
  • Child
  • Algorithms