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Metabolomics: a global biochemical approach to the study of central nervous system diseases.

Publication ,  Journal Article
Kaddurah-Daouk, R; Krishnan, KRR
Published in: Neuropsychopharmacology
January 2009

Metabolomics, the omics science of biochemistry, is a global approach to understanding regulation of metabolic pathways and metabolic networks of a biological system. Metabolomics complements data derived from genomics, transcriptomics, and proteomics to assist in providing a systems approach to the study of human health and disease. In this review we focus on applications of metabolomics for the study of diseases of the nervous system. We share concepts in metabolomics, tools used in metabolic profiling and early findings from the study of neuropsychiatric diseases, and drugs used to treat these diseases. Metabolomics emerges as another powerful tool in central nervous system research.

Duke Scholars

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Published In

Neuropsychopharmacology

DOI

EISSN

1740-634X

Publication Date

January 2009

Volume

34

Issue

1

Start / End Page

173 / 186

Location

England

Related Subject Headings

  • Psychiatry
  • Metabolomics
  • Mental Disorders
  • Humans
  • Central Nervous System Diseases
  • Biomarkers
  • Biological Psychiatry
  • Animals
  • 5202 Biological psychology
  • 3209 Neurosciences
 

Citation

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Chicago
ICMJE
MLA
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Kaddurah-Daouk, R., & Krishnan, K. R. R. (2009). Metabolomics: a global biochemical approach to the study of central nervous system diseases. Neuropsychopharmacology, 34(1), 173–186. https://doi.org/10.1038/npp.2008.174
Kaddurah-Daouk, Rima, and K Ranga Rama Krishnan. “Metabolomics: a global biochemical approach to the study of central nervous system diseases.Neuropsychopharmacology 34, no. 1 (January 2009): 173–86. https://doi.org/10.1038/npp.2008.174.
Kaddurah-Daouk R, Krishnan KRR. Metabolomics: a global biochemical approach to the study of central nervous system diseases. Neuropsychopharmacology. 2009 Jan;34(1):173–86.
Kaddurah-Daouk, Rima, and K. Ranga Rama Krishnan. “Metabolomics: a global biochemical approach to the study of central nervous system diseases.Neuropsychopharmacology, vol. 34, no. 1, Jan. 2009, pp. 173–86. Pubmed, doi:10.1038/npp.2008.174.
Kaddurah-Daouk R, Krishnan KRR. Metabolomics: a global biochemical approach to the study of central nervous system diseases. Neuropsychopharmacology. 2009 Jan;34(1):173–186.

Published In

Neuropsychopharmacology

DOI

EISSN

1740-634X

Publication Date

January 2009

Volume

34

Issue

1

Start / End Page

173 / 186

Location

England

Related Subject Headings

  • Psychiatry
  • Metabolomics
  • Mental Disorders
  • Humans
  • Central Nervous System Diseases
  • Biomarkers
  • Biological Psychiatry
  • Animals
  • 5202 Biological psychology
  • 3209 Neurosciences