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Phosphatases join kinases in DNA-damage response pathways.

Publication ,  Journal Article
Bakkenist, CJ; Kastan, MB
Published in: Trends Cell Biol
July 2004

An inappropriate imbalance of kinase and phosphatase activities could be deleterious to cellular processes such as proliferation. Cellular responses to DNA damage use signal-transduction pathways involving phosphorylation events, and such modifications must be reversible to make these responses transient, rather than permanent, events. Three recent articles describe roles for two phosphatases in signaling pathways that are activated after DNA damage.

Duke Scholars

Published In

Trends Cell Biol

DOI

ISSN

0962-8924

Publication Date

July 2004

Volume

14

Issue

7

Start / End Page

339 / 341

Location

England

Related Subject Headings

  • Signal Transduction
  • Schizosaccharomyces
  • Phosphotransferases
  • Phosphoric Monoester Hydrolases
  • Models, Biological
  • Developmental Biology
  • DNA Damage
  • 3101 Biochemistry and cell biology
  • 11 Medical and Health Sciences
  • 06 Biological Sciences
 

Citation

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Bakkenist, C. J., & Kastan, M. B. (2004). Phosphatases join kinases in DNA-damage response pathways. Trends Cell Biol, 14(7), 339–341. https://doi.org/10.1016/j.tcb.2004.05.001
Bakkenist, Christopher J., and Michael B. Kastan. “Phosphatases join kinases in DNA-damage response pathways.Trends Cell Biol 14, no. 7 (July 2004): 339–41. https://doi.org/10.1016/j.tcb.2004.05.001.
Bakkenist CJ, Kastan MB. Phosphatases join kinases in DNA-damage response pathways. Trends Cell Biol. 2004 Jul;14(7):339–41.
Bakkenist, Christopher J., and Michael B. Kastan. “Phosphatases join kinases in DNA-damage response pathways.Trends Cell Biol, vol. 14, no. 7, July 2004, pp. 339–41. Pubmed, doi:10.1016/j.tcb.2004.05.001.
Bakkenist CJ, Kastan MB. Phosphatases join kinases in DNA-damage response pathways. Trends Cell Biol. 2004 Jul;14(7):339–341.
Journal cover image

Published In

Trends Cell Biol

DOI

ISSN

0962-8924

Publication Date

July 2004

Volume

14

Issue

7

Start / End Page

339 / 341

Location

England

Related Subject Headings

  • Signal Transduction
  • Schizosaccharomyces
  • Phosphotransferases
  • Phosphoric Monoester Hydrolases
  • Models, Biological
  • Developmental Biology
  • DNA Damage
  • 3101 Biochemistry and cell biology
  • 11 Medical and Health Sciences
  • 06 Biological Sciences