Phosphatases join kinases in DNA-damage response pathways.
Publication
, Journal Article
Bakkenist, CJ; Kastan, MB
Published in: Trends Cell Biol
July 2004
An inappropriate imbalance of kinase and phosphatase activities could be deleterious to cellular processes such as proliferation. Cellular responses to DNA damage use signal-transduction pathways involving phosphorylation events, and such modifications must be reversible to make these responses transient, rather than permanent, events. Three recent articles describe roles for two phosphatases in signaling pathways that are activated after DNA damage.
Duke Scholars
Published In
Trends Cell Biol
DOI
ISSN
0962-8924
Publication Date
July 2004
Volume
14
Issue
7
Start / End Page
339 / 341
Location
England
Related Subject Headings
- Signal Transduction
- Schizosaccharomyces
- Phosphotransferases
- Phosphoric Monoester Hydrolases
- Models, Biological
- Developmental Biology
- DNA Damage
- 3101 Biochemistry and cell biology
- 11 Medical and Health Sciences
- 06 Biological Sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Bakkenist, C. J., & Kastan, M. B. (2004). Phosphatases join kinases in DNA-damage response pathways. Trends Cell Biol, 14(7), 339–341. https://doi.org/10.1016/j.tcb.2004.05.001
Bakkenist, Christopher J., and Michael B. Kastan. “Phosphatases join kinases in DNA-damage response pathways.” Trends Cell Biol 14, no. 7 (July 2004): 339–41. https://doi.org/10.1016/j.tcb.2004.05.001.
Bakkenist CJ, Kastan MB. Phosphatases join kinases in DNA-damage response pathways. Trends Cell Biol. 2004 Jul;14(7):339–41.
Bakkenist, Christopher J., and Michael B. Kastan. “Phosphatases join kinases in DNA-damage response pathways.” Trends Cell Biol, vol. 14, no. 7, July 2004, pp. 339–41. Pubmed, doi:10.1016/j.tcb.2004.05.001.
Bakkenist CJ, Kastan MB. Phosphatases join kinases in DNA-damage response pathways. Trends Cell Biol. 2004 Jul;14(7):339–341.
Published In
Trends Cell Biol
DOI
ISSN
0962-8924
Publication Date
July 2004
Volume
14
Issue
7
Start / End Page
339 / 341
Location
England
Related Subject Headings
- Signal Transduction
- Schizosaccharomyces
- Phosphotransferases
- Phosphoric Monoester Hydrolases
- Models, Biological
- Developmental Biology
- DNA Damage
- 3101 Biochemistry and cell biology
- 11 Medical and Health Sciences
- 06 Biological Sciences