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The relation of computer-based measures of sperm morphology and motility to male infertility.

Publication ,  Journal Article
Boyle, CA; Khoury, MJ; Katz, DF; Annest, JL; Kresnow, MJ; DeStefano, F; Schrader, SM
Published in: Epidemiology (Cambridge, Mass.)
May 1992

We investigated the relation between various sperm characteristics, including morphometric parameters, and impaired fertility among 596 men who participated in a national study. Semen was collected and processed by using a standardized protocol, and sperm measurements were made using a computer-aided sperm analysis instrument. We defined infertility in two ways: (1) the inability to father a child after trying for a year or longer, and (2) the number of children fathered. We found that all measures of sperm motion were decreased among men with impaired fertility. After adjustment for the other motion parameters and various potential confounders, however, only the percentage of progressive cells was associated with infertility. One morphometric parameter, the mean length/width ratio, was consistently associated with both measures of infertility, even after adjustment for potential covariates. This measure was also strongly associated with infertility among various subgroups defined by poor sperm concentration, motility, and morphology. The sperm length/width ratio appears to be an important correlate of infertility in males.

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Published In

Epidemiology (Cambridge, Mass.)

DOI

EISSN

1531-5487

ISSN

1044-3983

Publication Date

May 1992

Volume

3

Issue

3

Start / End Page

239 / 246

Related Subject Headings

  • United States
  • Spermatozoa
  • Sperm Motility
  • Sperm Count
  • Retrospective Studies
  • Random Allocation
  • Military Personnel
  • Male
  • Infertility, Male
  • Humans
 

Citation

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Boyle, C. A., Khoury, M. J., Katz, D. F., Annest, J. L., Kresnow, M. J., DeStefano, F., & Schrader, S. M. (1992). The relation of computer-based measures of sperm morphology and motility to male infertility. Epidemiology (Cambridge, Mass.), 3(3), 239–246. https://doi.org/10.1097/00001648-199205000-00009
Boyle, C. A., M. J. Khoury, D. F. Katz, J. L. Annest, M. J. Kresnow, F. DeStefano, and S. M. Schrader. “The relation of computer-based measures of sperm morphology and motility to male infertility.Epidemiology (Cambridge, Mass.) 3, no. 3 (May 1992): 239–46. https://doi.org/10.1097/00001648-199205000-00009.
Boyle CA, Khoury MJ, Katz DF, Annest JL, Kresnow MJ, DeStefano F, et al. The relation of computer-based measures of sperm morphology and motility to male infertility. Epidemiology (Cambridge, Mass). 1992 May;3(3):239–46.
Boyle, C. A., et al. “The relation of computer-based measures of sperm morphology and motility to male infertility.Epidemiology (Cambridge, Mass.), vol. 3, no. 3, May 1992, pp. 239–46. Epmc, doi:10.1097/00001648-199205000-00009.
Boyle CA, Khoury MJ, Katz DF, Annest JL, Kresnow MJ, DeStefano F, Schrader SM. The relation of computer-based measures of sperm morphology and motility to male infertility. Epidemiology (Cambridge, Mass). 1992 May;3(3):239–246.

Published In

Epidemiology (Cambridge, Mass.)

DOI

EISSN

1531-5487

ISSN

1044-3983

Publication Date

May 1992

Volume

3

Issue

3

Start / End Page

239 / 246

Related Subject Headings

  • United States
  • Spermatozoa
  • Sperm Motility
  • Sperm Count
  • Retrospective Studies
  • Random Allocation
  • Military Personnel
  • Male
  • Infertility, Male
  • Humans