Replication of linkage results using MALDI-TOF detection of single nucleotide polymorphisms (SNPS)
Publication
, Journal Article
Gundry, R; Hayden, D; Boyce, P; Voltz, A; Luong, E; Pugh, E; Kelley, M; Fan, R; Bailey-Wilson, JE; Witmer, D; Doheny, K
Published in: Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics
December 1, 2002
The utility of MALDI-TOF MS detection of single nucleotide polymorphisms (SNP) was discussed. The study was carried out by genotyped and analyzed 40 SNPs on chromosomes 22 using the Homogeneous Mass EXTEND (hME) assay in one large 4 generation family consisting of 26 individuals. It was observed that, for the chromosome 22 SNP assays analyzed, the assays were originally genotyped up to four times for a single assay. Three mismatched were also found among 1,451 comparisons that equal to 0.21% and the overall missing data after considering all attempts was 3.1%.
Duke Scholars
Published In
Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics
Publication Date
December 1, 2002
Start / End Page
399 / 401
Citation
APA
Chicago
ICMJE
MLA
NLM
Gundry, R., Hayden, D., Boyce, P., Voltz, A., Luong, E., Pugh, E., … Doheny, K. (2002). Replication of linkage results using MALDI-TOF detection of single nucleotide polymorphisms (SNPS). Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics, 399–401.
Gundry, R., D. Hayden, P. Boyce, A. Voltz, E. Luong, E. Pugh, M. Kelley, et al. “Replication of linkage results using MALDI-TOF detection of single nucleotide polymorphisms (SNPS).” Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics, December 1, 2002, 399–401.
Gundry R, Hayden D, Boyce P, Voltz A, Luong E, Pugh E, et al. Replication of linkage results using MALDI-TOF detection of single nucleotide polymorphisms (SNPS). Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics. 2002 Dec 1;399–401.
Gundry, R., et al. “Replication of linkage results using MALDI-TOF detection of single nucleotide polymorphisms (SNPS).” Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics, Dec. 2002, pp. 399–401.
Gundry R, Hayden D, Boyce P, Voltz A, Luong E, Pugh E, Kelley M, Fan R, Bailey-Wilson JE, Witmer D, Doheny K. Replication of linkage results using MALDI-TOF detection of single nucleotide polymorphisms (SNPS). Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics. 2002 Dec 1;399–401.
Published In
Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics
Publication Date
December 1, 2002
Start / End Page
399 / 401