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Barbed suture for gastrointestinal closure: a randomized control trial.

Publication ,  Journal Article
Demyttenaere, SV; Nau, P; Henn, M; Beck, C; Zaruby, J; Primavera, M; Kirsch, D; Miller, J; Liu, JJ; Bellizzi, A; Melvin, WS
Published in: Surg Innov
September 2009

In an effort to make laparoscopic suturing more efficient, the V-Loc advanced wound closure device (Covidien, Mansfield, MA) has been produced. This device is a self-anchoring barbed suture that obviates the need for knot tying. The goal of this initial feasibility study was to investigate the use of the barbed suture in gastrointestinal enterotomy closure. A randomized study of 12 pigs comparing enterotomy closure with barbed versus a nonbarbed suture of similar tensile strength was performed. To this end, 25 mm enterotomies were made in the stomach (1 control, 1 treatment), jejunum (2 controls, 2 treatments), and descending colon (1 control, 1 treatment). Animals were killed at 3, 7, and 14 days postoperatively (4 each group) and their gastrointestinal tracts harvested; 6 of the 8 enterotomies from each pig underwent burst strength testing. The remaining 2 were fixed in formalin and sent for histological examination. All 12 pigs survived until they were killed without any major complications. Enterotomy closure with barbed suture revealed adhesion scores, burst strength pressures, and histology scores that were similar to those for the control. Jejunal closures resulted in 6 failures at 7 days (3 control, 3 barbed) and 4 failures at 14 days (2 control, 2 barbed). The barbed suture significantly reduced suturing time in the stomach, jejunum, and colon. The V-Loc wound closure device appears to offer comparable gastrointestinal closure to 3-0 Maxon while being significantly faster. Further studies with V-Loc are required to assess its use in laparoscopic surgery.

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Published In

Surg Innov

DOI

ISSN

1553-3506

Publication Date

September 2009

Volume

16

Issue

3

Start / End Page

237 / 242

Location

United States

Related Subject Headings

  • Tensile Strength
  • Swine
  • Sutures
  • Suture Anchors
  • Surgery
  • Random Allocation
  • Jejunum
  • Female
  • Equipment Design
  • Duodenum
 

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Demyttenaere, S. V., Nau, P., Henn, M., Beck, C., Zaruby, J., Primavera, M., … Melvin, W. S. (2009). Barbed suture for gastrointestinal closure: a randomized control trial. Surg Innov, 16(3), 237–242. https://doi.org/10.1177/1553350609342988
Demyttenaere, Sebastian V., Peter Nau, Matthew Henn, Catherine Beck, Jeffrey Zaruby, Michael Primavera, David Kirsch, et al. “Barbed suture for gastrointestinal closure: a randomized control trial.Surg Innov 16, no. 3 (September 2009): 237–42. https://doi.org/10.1177/1553350609342988.
Demyttenaere SV, Nau P, Henn M, Beck C, Zaruby J, Primavera M, et al. Barbed suture for gastrointestinal closure: a randomized control trial. Surg Innov. 2009 Sep;16(3):237–42.
Demyttenaere, Sebastian V., et al. “Barbed suture for gastrointestinal closure: a randomized control trial.Surg Innov, vol. 16, no. 3, Sept. 2009, pp. 237–42. Pubmed, doi:10.1177/1553350609342988.
Demyttenaere SV, Nau P, Henn M, Beck C, Zaruby J, Primavera M, Kirsch D, Miller J, Liu JJ, Bellizzi A, Melvin WS. Barbed suture for gastrointestinal closure: a randomized control trial. Surg Innov. 2009 Sep;16(3):237–242.
Journal cover image

Published In

Surg Innov

DOI

ISSN

1553-3506

Publication Date

September 2009

Volume

16

Issue

3

Start / End Page

237 / 242

Location

United States

Related Subject Headings

  • Tensile Strength
  • Swine
  • Sutures
  • Suture Anchors
  • Surgery
  • Random Allocation
  • Jejunum
  • Female
  • Equipment Design
  • Duodenum