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Tribulin in post-traumatic stress disorder.

Publication ,  Journal Article
Davidson, J; Glover, V; Clow, A; Kudler, H; Meador, K; Sandler, M
Published in: Psychol Med
November 1988
Published version (DOI) Link to item

Tribulin (endogenous monoamine oxidase inhibitor/benzodiazepine receptor binding inhibitor) output was measured in the urine of 18 patients with post-traumatic stress disorder (PTSD) and 13 controls. The level of the two inhibitory activities was highly significantly correlated in the group as a whole. There was no difference between output of either inhibitor in patients and controls. However, when the PTSD group was subdivided according to various psychometric ratings, a pattern of output did emerge. Levels of both inhibitory activities were higher in agitated compared with non-agitated subjects, and lower in extroverts compared with introverts. This finding supports the view that tribulin output is raised in conditions of greater arousal.

Duke Scholars

Jonathan R.T. Davidson
Author Jonathan R.T. Davidson Psychiatry & Behavioral Sciences, Adult Psychiatry & Psychol ...
Harold S Kudler
Author Harold S Kudler Psychiatry & Behavioral Sciences, Adult Psychiatry & Psychol ...
Keith G. Meador
Author Keith G. Meador Psychiatry, Child & Family Mental Health & Community Psychia ...

Published In

Psychol Med

DOI

10.1017/s0033291700009764

ISSN

0033-2917

Publication Date

November 1988

Volume

18

Issue

4

Start / End Page

833 / 836

Location

England

Related Subject Headings

  • Stress Disorders, Post-Traumatic
  • Psychiatry
  • Monoamine Oxidase Inhibitors
  • Middle Aged
  • Male
  • Isatin
  • Humans
  • Female
  • Combat Disorders
  • Arousal
 

Citation

APA
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ICMJE
MLA
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Davidson, J., Glover, V., Clow, A., Kudler, H., Meador, K., & Sandler, M. (1988). Tribulin in post-traumatic stress disorder. Psychol Med, 18(4), 833–836. https://doi.org/10.1017/s0033291700009764
Davidson, J., V. Glover, A. Clow, H. Kudler, K. Meador, and M. Sandler. “Tribulin in post-traumatic stress disorder.” Psychol Med 18, no. 4 (November 1988): 833–36. https://doi.org/10.1017/s0033291700009764.
Davidson J, Glover V, Clow A, Kudler H, Meador K, Sandler M. Tribulin in post-traumatic stress disorder. Psychol Med. 1988 Nov;18(4):833–6.
Davidson, J., et al. “Tribulin in post-traumatic stress disorder.” Psychol Med, vol. 18, no. 4, Nov. 1988, pp. 833–36. Pubmed, doi:10.1017/s0033291700009764.
Davidson J, Glover V, Clow A, Kudler H, Meador K, Sandler M. Tribulin in post-traumatic stress disorder. Psychol Med. 1988 Nov;18(4):833–836.
Journal cover image

Published In

Psychol Med

DOI

10.1017/s0033291700009764

ISSN

0033-2917

Publication Date

November 1988

Volume

18

Issue

4

Start / End Page

833 / 836

Location

England

Related Subject Headings

  • Stress Disorders, Post-Traumatic
  • Psychiatry
  • Monoamine Oxidase Inhibitors
  • Middle Aged
  • Male
  • Isatin
  • Humans
  • Female
  • Combat Disorders
  • Arousal