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Prepartum, postpartum, and chronic depression effects on newborns.

Publication ,  Journal Article
Diego, MA; Field, T; Hernandez-Reif, M; Cullen, C; Schanberg, S; Kuhn, C
Published in: Psychiatry
2004

In order to assess the effects of the onset and chronicity of maternal depression on neonatal physiology, eighty pregnant women were assessed for depression during mid-pregnancy (M gestational age = 25.9 weeks) and shortly after delivery. The women were classified as reporting depressive symptoms 1) only during the prepartum assessment; 2) only during the postpartum assessment; 3) during both the prepartum and postpartum assessments; or 4) reporting no depressive symptoms at either the prepartum or the postpartum assessment. Maternal mood and biochemistry were assessed during pregnancy, and the EEG and biochemical characteristics of their 1-week-old infants were assessed shortly after birth. As predicted, the newborns of the mothers with prepartum and postpartum depressive symptoms had elevated cortisol and norepinephrine levels, lower dopamine levels, and greater relative right frontal EEG asymmetry. The infants in the prepartum group also showed greater relative right frontal EEG asymmetry and higher norepinephrine levels. These data suggest that effects on newborn physiology depend more on prepartum than postpartum maternal depression but may also depend on the duration of the depressive symptoms.

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Published In

Psychiatry

DOI

ISSN

0033-2747

Publication Date

2004

Volume

67

Issue

1

Start / End Page

63 / 80

Location

United States

Related Subject Headings

  • Stress Disorders, Post-Traumatic
  • Pregnancy Trimester, Third
  • Pregnancy Complications
  • Pregnancy
  • Perinatology
  • Mothers
  • Infant, Newborn
  • Humans
  • Frontal Lobe
  • Female
 

Citation

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Diego, M. A., Field, T., Hernandez-Reif, M., Cullen, C., Schanberg, S., & Kuhn, C. (2004). Prepartum, postpartum, and chronic depression effects on newborns. Psychiatry, 67(1), 63–80. https://doi.org/10.1521/psyc.67.1.63.31251
Diego, Miguel A., Tiffany Field, Maria Hernandez-Reif, Christy Cullen, Saul Schanberg, and Cynthia Kuhn. “Prepartum, postpartum, and chronic depression effects on newborns.Psychiatry 67, no. 1 (2004): 63–80. https://doi.org/10.1521/psyc.67.1.63.31251.
Diego MA, Field T, Hernandez-Reif M, Cullen C, Schanberg S, Kuhn C. Prepartum, postpartum, and chronic depression effects on newborns. Psychiatry. 2004;67(1):63–80.
Diego, Miguel A., et al. “Prepartum, postpartum, and chronic depression effects on newborns.Psychiatry, vol. 67, no. 1, 2004, pp. 63–80. Pubmed, doi:10.1521/psyc.67.1.63.31251.
Diego MA, Field T, Hernandez-Reif M, Cullen C, Schanberg S, Kuhn C. Prepartum, postpartum, and chronic depression effects on newborns. Psychiatry. 2004;67(1):63–80.

Published In

Psychiatry

DOI

ISSN

0033-2747

Publication Date

2004

Volume

67

Issue

1

Start / End Page

63 / 80

Location

United States

Related Subject Headings

  • Stress Disorders, Post-Traumatic
  • Pregnancy Trimester, Third
  • Pregnancy Complications
  • Pregnancy
  • Perinatology
  • Mothers
  • Infant, Newborn
  • Humans
  • Frontal Lobe
  • Female