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Higher levels of CSF homovanillic acid in recently abstinent cocaine-dependent patients.

Publication ,  Journal Article
Roy, A; Berman, J; Williams, R; Kuhn, C; Gonzalez, B
Published in: Am J Psychiatry
June 2002

OBJECTIVE: The authors examined an index of dopaminergic neurotransmission in recently abstinent cocaine-dependent patients. METHOD: CSF concentrations of the dopamine metabolite homovanillic acid (HVA) were determined in 30 recently abstinent cocaine-dependent patients and 69 healthy comparison subjects. RESULTS: The cocaine-dependent patients had a significantly higher mean concentration of CSF HVA than did the healthy comparison group. CONCLUSIONS: Recently abstinent cocaine-dependent patients may show dysregulation of the central dopaminergic system.

Duke Scholars

Published In

Am J Psychiatry

DOI

ISSN

0002-953X

Publication Date

June 2002

Volume

159

Issue

6

Start / End Page

1053 / 1055

Location

United States

Related Subject Headings

  • Synaptic Transmission
  • Psychiatry
  • Middle Aged
  • Male
  • Humans
  • Hospitalization
  • Homovanillic Acid
  • Dopamine
  • Cocaine-Related Disorders
  • Brain
 

Citation

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Chicago
ICMJE
MLA
NLM
Roy, A., Berman, J., Williams, R., Kuhn, C., & Gonzalez, B. (2002). Higher levels of CSF homovanillic acid in recently abstinent cocaine-dependent patients. Am J Psychiatry, 159(6), 1053–1055. https://doi.org/10.1176/appi.ajp.159.6.1053
Roy, Alec, Jeffrey Berman, Redford Williams, Cynthia Kuhn, and Bienvenido Gonzalez. “Higher levels of CSF homovanillic acid in recently abstinent cocaine-dependent patients.Am J Psychiatry 159, no. 6 (June 2002): 1053–55. https://doi.org/10.1176/appi.ajp.159.6.1053.
Roy A, Berman J, Williams R, Kuhn C, Gonzalez B. Higher levels of CSF homovanillic acid in recently abstinent cocaine-dependent patients. Am J Psychiatry. 2002 Jun;159(6):1053–5.
Roy, Alec, et al. “Higher levels of CSF homovanillic acid in recently abstinent cocaine-dependent patients.Am J Psychiatry, vol. 159, no. 6, June 2002, pp. 1053–55. Pubmed, doi:10.1176/appi.ajp.159.6.1053.
Roy A, Berman J, Williams R, Kuhn C, Gonzalez B. Higher levels of CSF homovanillic acid in recently abstinent cocaine-dependent patients. Am J Psychiatry. 2002 Jun;159(6):1053–1055.
Journal cover image

Published In

Am J Psychiatry

DOI

ISSN

0002-953X

Publication Date

June 2002

Volume

159

Issue

6

Start / End Page

1053 / 1055

Location

United States

Related Subject Headings

  • Synaptic Transmission
  • Psychiatry
  • Middle Aged
  • Male
  • Humans
  • Hospitalization
  • Homovanillic Acid
  • Dopamine
  • Cocaine-Related Disorders
  • Brain