Arrestins as signaling molecules involved in apoptotic pathways: a real eye opener.
Publication
, Journal Article
Miller, WE; Lefkowitz, RJ
Published in: Sci STKE
February 13, 2001
Recent data suggest that internalized receptor and arrestin complexes are actively involved in signal transduction. Miller and Lefkowitz discuss evidence from the Drosophila visual system that suggests that intracellular rhodopsin and arrestin2 complexes induce apoptosis. Experiments with activated mammalian G protein-coupled receptor and arrestin complexes point to a mechanism by which proliferative or proapoptotic signals can be mediated largely independent from G protein activation.
Duke Scholars
Published In
Sci STKE
DOI
EISSN
1525-8882
Publication Date
February 13, 2001
Volume
2001
Issue
69
Start / End Page
pe1
Location
United States
Related Subject Headings
- Signal Transduction
- Humans
- Arrestins
- Apoptosis
- Animals
Citation
APA
Chicago
ICMJE
MLA
NLM
Miller, W. E., & Lefkowitz, R. J. (2001). Arrestins as signaling molecules involved in apoptotic pathways: a real eye opener. Sci STKE, 2001(69), pe1. https://doi.org/10.1126/stke.2001.69.pe1
Miller, W. E., and R. J. Lefkowitz. “Arrestins as signaling molecules involved in apoptotic pathways: a real eye opener.” Sci STKE 2001, no. 69 (February 13, 2001): pe1. https://doi.org/10.1126/stke.2001.69.pe1.
Miller WE, Lefkowitz RJ. Arrestins as signaling molecules involved in apoptotic pathways: a real eye opener. Sci STKE. 2001 Feb 13;2001(69):pe1.
Miller, W. E., and R. J. Lefkowitz. “Arrestins as signaling molecules involved in apoptotic pathways: a real eye opener.” Sci STKE, vol. 2001, no. 69, Feb. 2001, p. pe1. Pubmed, doi:10.1126/stke.2001.69.pe1.
Miller WE, Lefkowitz RJ. Arrestins as signaling molecules involved in apoptotic pathways: a real eye opener. Sci STKE. 2001 Feb 13;2001(69):pe1.
Published In
Sci STKE
DOI
EISSN
1525-8882
Publication Date
February 13, 2001
Volume
2001
Issue
69
Start / End Page
pe1
Location
United States
Related Subject Headings
- Signal Transduction
- Humans
- Arrestins
- Apoptosis
- Animals