Skip to main content
Journal cover image

Anthropometric measures after Fontan procedure: implications for suboptimal functional outcome.

Publication ,  Journal Article
Cohen, MS; Zak, V; Atz, AM; Printz, BF; Pinto, N; Lambert, L; Pemberton, V; Li, JS; Margossian, R; Dunbar-Masterson, C; McCrindle, BW
Published in: Am Heart J
December 2010

BACKGROUND: Abnormal height and adiposity are observed after the Fontan operation. These abnormalities may be associated with worse functional outcome. METHODS: We analyzed data from the National Heart, Lung, and Blood Institute Pediatric Heart Network cross-sectional study of Fontan patients. Groups were defined by height (z-score<-1.5 or≥-1.5) and body mass index (body mass index [BMI] z-score<-1.5 or -1.5 to 1.5 or≥1.5). Associations of anthropometric measures with measurements from clinical testing (exercise, echocardiography, magnetic resonance imaging) were determined adjusting for demographics, anatomy, and pre-Fontan status. Relationships between anthropometric measures and functional health status (FHS) were assessed using the Child Health Questionnaire. RESULTS: Mean age of the cohort (n=544) was 11.9±3.4 years. Lower height-z patients (n=124, 23%) were more likely to have pre-Fontan atrioventricular valve regurgitation (P=.029), as well as orthopedic and developmental problems (both P<.001). Lower height-z patients also had lower physical and psychosocial FHS summary scores (both P<.01). Higher BMI-z patients (n=45, 8%) and lower BMI-z patients (n=53, 10%) did not have worse FHS compared to midrange BMI-z patients (n=446, 82%). However, higher BMI-z patients had higher ventricular mass-to-volume ratio (P=.03) and lower % predicted maximum work (P=.004) compared to midrange and lower BMI-z patients. CONCLUSIONS: Abnormal anthropometry is common in Fontan patients. Shorter stature is associated with poorer FHS and non-cardiac problems. Increased adiposity is associated with more ventricular hypertrophy and poorer exercise performance, which may have significant long-term implications in this at-risk population.

Duke Scholars

Published In

Am Heart J

DOI

EISSN

1097-6744

Publication Date

December 2010

Volume

160

Issue

6

Start / End Page

1092 / 1098.e1

Location

United States

Related Subject Headings

  • Surveys and Questionnaires
  • Risk Factors
  • Postoperative Period
  • Overweight
  • Male
  • Magnetic Resonance Imaging
  • Hypertrophy, Left Ventricular
  • Humans
  • Heart Defects, Congenital
  • Fontan Procedure
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Cohen, M. S., Zak, V., Atz, A. M., Printz, B. F., Pinto, N., Lambert, L., … McCrindle, B. W. (2010). Anthropometric measures after Fontan procedure: implications for suboptimal functional outcome. Am Heart J, 160(6), 1092-1098.e1. https://doi.org/10.1016/j.ahj.2010.07.039
Cohen, Meryl S., Victor Zak, Andrew M. Atz, Beth F. Printz, Nelangi Pinto, Linda Lambert, Victoria Pemberton, et al. “Anthropometric measures after Fontan procedure: implications for suboptimal functional outcome.Am Heart J 160, no. 6 (December 2010): 1092-1098.e1. https://doi.org/10.1016/j.ahj.2010.07.039.
Cohen MS, Zak V, Atz AM, Printz BF, Pinto N, Lambert L, et al. Anthropometric measures after Fontan procedure: implications for suboptimal functional outcome. Am Heart J. 2010 Dec;160(6):1092-1098.e1.
Cohen, Meryl S., et al. “Anthropometric measures after Fontan procedure: implications for suboptimal functional outcome.Am Heart J, vol. 160, no. 6, Dec. 2010, pp. 1092-1098.e1. Pubmed, doi:10.1016/j.ahj.2010.07.039.
Cohen MS, Zak V, Atz AM, Printz BF, Pinto N, Lambert L, Pemberton V, Li JS, Margossian R, Dunbar-Masterson C, McCrindle BW. Anthropometric measures after Fontan procedure: implications for suboptimal functional outcome. Am Heart J. 2010 Dec;160(6):1092-1098.e1.
Journal cover image

Published In

Am Heart J

DOI

EISSN

1097-6744

Publication Date

December 2010

Volume

160

Issue

6

Start / End Page

1092 / 1098.e1

Location

United States

Related Subject Headings

  • Surveys and Questionnaires
  • Risk Factors
  • Postoperative Period
  • Overweight
  • Male
  • Magnetic Resonance Imaging
  • Hypertrophy, Left Ventricular
  • Humans
  • Heart Defects, Congenital
  • Fontan Procedure