Critical pathway for administering high-dose chemotherapy followed by peripheral blood stem cell rescue in the outpatient setting.

PURPOSE/OBJECTIVES: To explain the rationale and process of outpatient critical pathway development for sequential high-dose chemotherapy followed by peripheral blood stem cell transplantation. DATA SOURCES: Published books and journal articles. DATA SYNTHESIS: Complex treatment for patients with metastatic breast cancer is shifting to the outpatient area. To make this therapy safe and cost effective, a process for monitoring this type of outpatient care needs to be developed. CONCLUSIONS: Collaboration with a multidisciplinary team is important in ensuring quality of care for complex outpatient treatment protocols. Critical pathway development can serve as a road map for delivering this care. IMPLICATIONS FOR NURSING PRACTICE: As team leaders, nurses should oversee the critical pathway development and implementation. Nurses also should maintain their role of patient advocacy through monitoring pathway compliance.

Duke Scholars

Author Gwynn Douglas Long Medicine, Hematologic Malignancies and Cellular Therapy