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Dental lesions in tumoral calcinosis.

Publication ,  Journal Article
Burkes, EJ; Lyles, KW; Dolan, EA; Giammara, B; Hanker, J
Published in: J Oral Pathol Med
May 1991

Tumoral calcinosis (TC) is a rare inherited autosomal dominant metabolic disease manifested by elevated serum phosphorus and 1,25 dihydroxyvitamin D levels and periarticular cystic and solid tumorous calcifications. The dental findings in a large family have been critical in determining the genetic transmission of the condition. Radiographically the teeth have short bulbous roots, pulp stones and partial obliteration of the pulp cavity. Histologically, coronal dentin and a variable amount of radicular dentin appears to be deposited regularly. At nonspecific points the developing radicular dentin appears to encounter a mass of calcified material and proceed to grow around it. This mass has a unique histologic pattern with ovoid spaces surrounded by amorphous calcification. At levels of further root development the radicular dentin has an irregular bending tubule arrangement. The dental lesion of TC appears to be different from that of radicular dentin dysplasia in histologic structure and in the method of initiation of the dentin defect. These data suggest that the specific dental lesion is a new phenotypic marker for TC.

Duke Scholars

Published In

J Oral Pathol Med

DOI

ISSN

0904-2512

Publication Date

May 1991

Volume

20

Issue

5

Start / End Page

222 / 227

Location

Denmark

Related Subject Headings

  • Tooth Root
  • Tooth Abnormalities
  • Phenotype
  • Periodontal Diseases
  • Pedigree
  • Middle Aged
  • Male
  • Joint Diseases
  • Humans
  • Female
 

Citation

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Burkes, E. J., Lyles, K. W., Dolan, E. A., Giammara, B., & Hanker, J. (1991). Dental lesions in tumoral calcinosis. J Oral Pathol Med, 20(5), 222–227. https://doi.org/10.1111/j.1600-0714.1991.tb00423.x
Burkes, E. J., K. W. Lyles, E. A. Dolan, B. Giammara, and J. Hanker. “Dental lesions in tumoral calcinosis.J Oral Pathol Med 20, no. 5 (May 1991): 222–27. https://doi.org/10.1111/j.1600-0714.1991.tb00423.x.
Burkes EJ, Lyles KW, Dolan EA, Giammara B, Hanker J. Dental lesions in tumoral calcinosis. J Oral Pathol Med. 1991 May;20(5):222–7.
Burkes, E. J., et al. “Dental lesions in tumoral calcinosis.J Oral Pathol Med, vol. 20, no. 5, May 1991, pp. 222–27. Pubmed, doi:10.1111/j.1600-0714.1991.tb00423.x.
Burkes EJ, Lyles KW, Dolan EA, Giammara B, Hanker J. Dental lesions in tumoral calcinosis. J Oral Pathol Med. 1991 May;20(5):222–227.
Journal cover image

Published In

J Oral Pathol Med

DOI

ISSN

0904-2512

Publication Date

May 1991

Volume

20

Issue

5

Start / End Page

222 / 227

Location

Denmark

Related Subject Headings

  • Tooth Root
  • Tooth Abnormalities
  • Phenotype
  • Periodontal Diseases
  • Pedigree
  • Middle Aged
  • Male
  • Joint Diseases
  • Humans
  • Female