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Cerebral phaeohyphomycosis complicated with brain abscess: a case report.

Publication ,  Journal Article
Lirng, JF; Tien, RD; Osumi, AK; Madden, JF; McLendon, RP; Sexton, D
Published in: Zhonghua Yi Xue Za Zhi (Taipei)
June 1995

Cerebral phaeohyphomycosis is used to describe the rare clinical syndrome of cerebral infection caused by dematiaceous (i.e. pigmented olivaceous-brown) fungi. It usually presents as brain abscess. In view of the rarity of this fungal infection and its clinical importance, we report a case of cerebral phaeohyphomycosis caused by Xylohypha bantiana. The patient presented with a seizure attack. The MRI study revealed a ring-enhancing lesion with marked perifocal edema in right high frontoparietal junction of the brain. He underwent an initial craniotomy for removal of the lesion and a second craniotomy for recurrence of the lesion 3 months later. The diagnosis was based on successful cultivation of X. bantiana from the surgical specimen and on histopathology. The patient received antifungal drug therapy of 5-flucytosine and itraconazole. He has done well without any symptoms. We think complete surgical removal of the brain abscess combined with antifungal drug therapy is the best management for this rare fungal disease.

Duke Scholars

Published In

Zhonghua Yi Xue Za Zhi (Taipei)

ISSN

0578-1337

Publication Date

June 1995

Volume

55

Issue

6

Start / End Page

491 / 495

Location

China (Republic : 1949- )

Related Subject Headings

  • Mycoses
  • Mitosporic Fungi
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
  • Humans
  • General & Internal Medicine
  • Brain Abscess
 

Citation

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Lirng, J. F., Tien, R. D., Osumi, A. K., Madden, J. F., McLendon, R. P., & Sexton, D. (1995). Cerebral phaeohyphomycosis complicated with brain abscess: a case report. Zhonghua Yi Xue Za Zhi (Taipei), 55(6), 491–495.
Lirng, J. F., R. D. Tien, A. K. Osumi, J. F. Madden, R. P. McLendon, and D. Sexton. “Cerebral phaeohyphomycosis complicated with brain abscess: a case report.Zhonghua Yi Xue Za Zhi (Taipei) 55, no. 6 (June 1995): 491–95.
Lirng JF, Tien RD, Osumi AK, Madden JF, McLendon RP, Sexton D. Cerebral phaeohyphomycosis complicated with brain abscess: a case report. Zhonghua Yi Xue Za Zhi (Taipei). 1995 Jun;55(6):491–5.
Lirng, J. F., et al. “Cerebral phaeohyphomycosis complicated with brain abscess: a case report.Zhonghua Yi Xue Za Zhi (Taipei), vol. 55, no. 6, June 1995, pp. 491–95.
Lirng JF, Tien RD, Osumi AK, Madden JF, McLendon RP, Sexton D. Cerebral phaeohyphomycosis complicated with brain abscess: a case report. Zhonghua Yi Xue Za Zhi (Taipei). 1995 Jun;55(6):491–495.

Published In

Zhonghua Yi Xue Za Zhi (Taipei)

ISSN

0578-1337

Publication Date

June 1995

Volume

55

Issue

6

Start / End Page

491 / 495

Location

China (Republic : 1949- )

Related Subject Headings

  • Mycoses
  • Mitosporic Fungi
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
  • Humans
  • General & Internal Medicine
  • Brain Abscess