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Focal nodular hyperplasia-like lesions in patients with cavernous transformation of the portal vein: prevalence, MR findings and natural history.

Publication ,  Journal Article
Marin, D; Galluzzo, A; Plessier, A; Brancatelli, G; Valla, D; Vilgrain, V
Published in: Eur Radiol
October 2011

PURPOSE: To retrospectively investigate the prevalence, MR findings, natural history, and association with other hepatic lesions of focal nodular hyperplasia (FNH)-like lesions in a cohort of consecutive patients with cavernous transformation of the portal vein (CTPV). MATERIALS AND METHODS: This retrospective IRB-approved study comprised 58 patients (32 men, 26 women; average age, 50 years) with CTPV who underwent liver MR imaging between 2000 and 2008. MR images were assessed by two radiologists in consensus for the presence of (a) FNH-like lesions and other liver lesions, and (b) other imaging findings. Patients were assigned to a stable or progressive clinical course based on lesion characteristics at follow-up. RESULTS: Twelve of 58 patients (21%) had 38 FNH-like lesions (average size, 1.3 cm). Common findings of FNH-like lesions were isointensity on T2-weighted images (82%), intense and homogeneous enhancement during the arterial phase, and lack of washout during the hepatic venous and interstitial phases (100%). FNH-like lesions were found with other benign liver lesions (1 hemangioma, 1 adenoma) in two patients. Three (25%) patients with FNH-like lesions showed a progressive clinical course. CONCLUSION: FNH-like lesions are commonly detected in patients with CTPV. Most lesions demonstrate benign imaging findings and stable clinical course.

Duke Scholars

Published In

Eur Radiol

DOI

EISSN

1432-1084

Publication Date

October 2011

Volume

21

Issue

10

Start / End Page

2074 / 2082

Location

Germany

Related Subject Headings

  • Treatment Outcome
  • Retrospective Studies
  • Reference Values
  • Portal Vein
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
  • Liver Neoplasms
  • Image Processing, Computer-Assisted
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Marin, D., Galluzzo, A., Plessier, A., Brancatelli, G., Valla, D., & Vilgrain, V. (2011). Focal nodular hyperplasia-like lesions in patients with cavernous transformation of the portal vein: prevalence, MR findings and natural history. Eur Radiol, 21(10), 2074–2082. https://doi.org/10.1007/s00330-011-2161-z
Marin, Daniele, Anna Galluzzo, Aurélie Plessier, Giuseppe Brancatelli, Dominique Valla, and Valérie Vilgrain. “Focal nodular hyperplasia-like lesions in patients with cavernous transformation of the portal vein: prevalence, MR findings and natural history.Eur Radiol 21, no. 10 (October 2011): 2074–82. https://doi.org/10.1007/s00330-011-2161-z.
Marin D, Galluzzo A, Plessier A, Brancatelli G, Valla D, Vilgrain V. Focal nodular hyperplasia-like lesions in patients with cavernous transformation of the portal vein: prevalence, MR findings and natural history. Eur Radiol. 2011 Oct;21(10):2074–82.
Marin, Daniele, et al. “Focal nodular hyperplasia-like lesions in patients with cavernous transformation of the portal vein: prevalence, MR findings and natural history.Eur Radiol, vol. 21, no. 10, Oct. 2011, pp. 2074–82. Pubmed, doi:10.1007/s00330-011-2161-z.
Marin D, Galluzzo A, Plessier A, Brancatelli G, Valla D, Vilgrain V. Focal nodular hyperplasia-like lesions in patients with cavernous transformation of the portal vein: prevalence, MR findings and natural history. Eur Radiol. 2011 Oct;21(10):2074–2082.
Journal cover image

Published In

Eur Radiol

DOI

EISSN

1432-1084

Publication Date

October 2011

Volume

21

Issue

10

Start / End Page

2074 / 2082

Location

Germany

Related Subject Headings

  • Treatment Outcome
  • Retrospective Studies
  • Reference Values
  • Portal Vein
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
  • Liver Neoplasms
  • Image Processing, Computer-Assisted