Engineered microsphere contrast agents for optical coherence tomography.
Publication
, Journal Article
Lee, TM; Oldenburg, AL; Sitafalwalla, S; Marks, DL; Luo, W; Toublan, FJ-J; Suslick, KS; Boppart, SA
Published in: Optics letters
September 2003
Contrast agents are utilized in virtually every imaging modality to enhance diagnostic capabilities. We introduce a novel class of optical contrast agent, namely, encapsulating microspheres, that are based not on fluorescence but on scattering nanoparticles within the shell or core. The agents are suitable for reflection- or scattering-based techniques such as optical coherence tomography, light microscopy, and reflectance confocal microscopy. We characterize the optical properties of gold-, melanin-, and carbon-shelled contrast agents and demonstrate enhancement of optical coherence tomography imaging after intravenous injection of such an agent into a mouse.
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Published In
Optics letters
DOI
EISSN
1539-4794
ISSN
0146-9592
Publication Date
September 2003
Volume
28
Issue
17
Start / End Page
1546 / 1548
Related Subject Headings
- Tomography
- Optics and Photonics
- Optics
- Nanotechnology
- Microspheres
- Mice
- Male
- Liver
- Contrast Media
- Animals
Citation
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ICMJE
MLA
NLM
Lee, T. M., Oldenburg, A. L., Sitafalwalla, S., Marks, D. L., Luo, W., Toublan, F.-J., … Boppart, S. A. (2003). Engineered microsphere contrast agents for optical coherence tomography. Optics Letters, 28(17), 1546–1548. https://doi.org/10.1364/ol.28.001546
Lee, Tin Man, Amy L. Oldenburg, Shoeb Sitafalwalla, Daniel L. Marks, Wei Luo, Farah Jean-Jacques Toublan, Kenneth S. Suslick, and Stephen A. Boppart. “Engineered microsphere contrast agents for optical coherence tomography.” Optics Letters 28, no. 17 (September 2003): 1546–48. https://doi.org/10.1364/ol.28.001546.
Lee TM, Oldenburg AL, Sitafalwalla S, Marks DL, Luo W, Toublan FJ-J, et al. Engineered microsphere contrast agents for optical coherence tomography. Optics letters. 2003 Sep;28(17):1546–8.
Lee, Tin Man, et al. “Engineered microsphere contrast agents for optical coherence tomography.” Optics Letters, vol. 28, no. 17, Sept. 2003, pp. 1546–48. Epmc, doi:10.1364/ol.28.001546.
Lee TM, Oldenburg AL, Sitafalwalla S, Marks DL, Luo W, Toublan FJ-J, Suslick KS, Boppart SA. Engineered microsphere contrast agents for optical coherence tomography. Optics letters. 2003 Sep;28(17):1546–1548.
Published In
Optics letters
DOI
EISSN
1539-4794
ISSN
0146-9592
Publication Date
September 2003
Volume
28
Issue
17
Start / End Page
1546 / 1548
Related Subject Headings
- Tomography
- Optics and Photonics
- Optics
- Nanotechnology
- Microspheres
- Mice
- Male
- Liver
- Contrast Media
- Animals