RAMP like proteins : RTP and REEP family of proteins.
Publication
, Journal Article
Mainland, J; Matsunami, H
Published in: Adv Exp Med Biol
2012
Mammalian odorant receptors (ORs) are typically retained in the endoplasmic reticulum (ER) when expressed in heterologous cells. The RTP (Receptor-Transporting Protein) and REEP (Receptor Expression Enhancing Protein) family of proteins were first identified as partners for ORs, promoting cell-surface expression and leading to functional responses in heterologous cell systems. Like RAMPs, the RTP and REEP proteins appear to partner with GPCRs to promote cell-surface expression. Unlike RAMPs, they do not appear to alter the pharmacology of the partner receptor.
Duke Scholars
Published In
Adv Exp Med Biol
DOI
ISSN
0065-2598
Publication Date
2012
Volume
744
Start / End Page
75 / 86
Location
United States
Related Subject Headings
- Sequence Homology, Amino Acid
- Receptors, Odorant
- Molecular Sequence Data
- Humans
- General & Internal Medicine
- Animals
- Amino Acid Sequence
- 32 Biomedical and clinical sciences
- 31 Biological sciences
- 11 Medical and Health Sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Mainland, J., & Matsunami, H. (2012). RAMP like proteins : RTP and REEP family of proteins. Adv Exp Med Biol, 744, 75–86. https://doi.org/10.1007/978-1-4614-2364-5_7
Mainland, Joel, and Hiroaki Matsunami. “RAMP like proteins : RTP and REEP family of proteins.” Adv Exp Med Biol 744 (2012): 75–86. https://doi.org/10.1007/978-1-4614-2364-5_7.
Mainland J, Matsunami H. RAMP like proteins : RTP and REEP family of proteins. Adv Exp Med Biol. 2012;744:75–86.
Mainland, Joel, and Hiroaki Matsunami. “RAMP like proteins : RTP and REEP family of proteins.” Adv Exp Med Biol, vol. 744, 2012, pp. 75–86. Pubmed, doi:10.1007/978-1-4614-2364-5_7.
Mainland J, Matsunami H. RAMP like proteins : RTP and REEP family of proteins. Adv Exp Med Biol. 2012;744:75–86.
Published In
Adv Exp Med Biol
DOI
ISSN
0065-2598
Publication Date
2012
Volume
744
Start / End Page
75 / 86
Location
United States
Related Subject Headings
- Sequence Homology, Amino Acid
- Receptors, Odorant
- Molecular Sequence Data
- Humans
- General & Internal Medicine
- Animals
- Amino Acid Sequence
- 32 Biomedical and clinical sciences
- 31 Biological sciences
- 11 Medical and Health Sciences