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An adaptive incremental approach to constructing ensemble classifiers: application in an information-theoretic computer-aided decision system for detection of masses in mammograms.

Publication ,  Journal Article
Mazurowski, MA; Zurada, JM; Tourassi, GD
Published in: Med Phys
July 2009

Ensemble classifiers have been shown efficient in multiple applications. In this article, the authors explore the effectiveness of ensemble classifiers in a case-based computer-aided diagnosis system for detection of masses in mammograms. They evaluate two general ways of constructing subclassifiers by resampling of the available development dataset: Random division and random selection. Furthermore, they discuss the problem of selecting the ensemble size and propose two adaptive incremental techniques that automatically select the size for the problem at hand. All the techniques are evaluated with respect to a previously proposed information-theoretic CAD system (IT-CAD). The experimental results show that the examined ensemble techniques provide a statistically significant improvement (AUC = 0.905 +/- 0.024) in performance as compared to the original IT-CAD system (AUC = 0.865 +/- 0.029). Some of the techniques allow for a notable reduction in the total number of examples stored in the case base (to 1.3% of the original size), which, in turn, results in lower storage requirements and a shorter response time of the system. Among the methods examined in this article, the two proposed adaptive techniques are by far the most effective for this purpose. Furthermore, the authors provide some discussion and guidance for choosing the ensemble parameters.

Duke Scholars

Published In

Med Phys

DOI

ISSN

0094-2405

Publication Date

July 2009

Volume

36

Issue

7

Start / End Page

2976 / 2984

Location

United States

Related Subject Headings

  • Reproducibility of Results
  • Nuclear Medicine & Medical Imaging
  • Mammography
  • Image Interpretation, Computer-Assisted
  • Humans
  • Female
  • Diagnosis, Computer-Assisted
  • Databases, Factual
  • Breast Neoplasms
  • Automation
 

Published In

Med Phys

DOI

ISSN

0094-2405

Publication Date

July 2009

Volume

36

Issue

7

Start / End Page

2976 / 2984

Location

United States

Related Subject Headings

  • Reproducibility of Results
  • Nuclear Medicine & Medical Imaging
  • Mammography
  • Image Interpretation, Computer-Assisted
  • Humans
  • Female
  • Diagnosis, Computer-Assisted
  • Databases, Factual
  • Breast Neoplasms
  • Automation