Skip to main content
Journal cover image

Facile syntheses of conformationally constrained analogues of lysine and homoglutamic acid

Publication ,  Journal Article
Barkallah, S; Schneider, SL; McCafferty, DG
Published in: Tetrahedron Letters
July 25, 2005

A facile divergent synthesis of the novel amino acid trans-4-aminoethyl-l- proline and trans-4-carboxymethyl-l-proline from commercially available trans-4-hydroxy-l-proline was developed. These conformationally constrained analogues of l-lysine and l-homoglutamic acid are useful proline templated amino acids (PTAAs) with potential applications in protein engineering and de novo protein design. © 2005 Elsevier Ltd. All rights reserved.

Duke Scholars

Published In

Tetrahedron Letters

DOI

ISSN

0040-4039

Publication Date

July 25, 2005

Volume

46

Issue

30

Start / End Page

4985 / 4987

Related Subject Headings

  • Organic Chemistry
  • 0305 Organic Chemistry
  • 0304 Medicinal and Biomolecular Chemistry
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Barkallah, S., Schneider, S. L., & McCafferty, D. G. (2005). Facile syntheses of conformationally constrained analogues of lysine and homoglutamic acid. Tetrahedron Letters, 46(30), 4985–4987. https://doi.org/10.1016/j.tetlet.2005.05.093
Barkallah, S., S. L. Schneider, and D. G. McCafferty. “Facile syntheses of conformationally constrained analogues of lysine and homoglutamic acid.” Tetrahedron Letters 46, no. 30 (July 25, 2005): 4985–87. https://doi.org/10.1016/j.tetlet.2005.05.093.
Barkallah S, Schneider SL, McCafferty DG. Facile syntheses of conformationally constrained analogues of lysine and homoglutamic acid. Tetrahedron Letters. 2005 Jul 25;46(30):4985–7.
Barkallah, S., et al. “Facile syntheses of conformationally constrained analogues of lysine and homoglutamic acid.” Tetrahedron Letters, vol. 46, no. 30, July 2005, pp. 4985–87. Scopus, doi:10.1016/j.tetlet.2005.05.093.
Barkallah S, Schneider SL, McCafferty DG. Facile syntheses of conformationally constrained analogues of lysine and homoglutamic acid. Tetrahedron Letters. 2005 Jul 25;46(30):4985–4987.
Journal cover image

Published In

Tetrahedron Letters

DOI

ISSN

0040-4039

Publication Date

July 25, 2005

Volume

46

Issue

30

Start / End Page

4985 / 4987

Related Subject Headings

  • Organic Chemistry
  • 0305 Organic Chemistry
  • 0304 Medicinal and Biomolecular Chemistry