A case of frontal neuropsychological and neuroimaging signs following multiple primary-blast exposure.
Blast-related traumatic brain injury (TBI) from the Afghanistan and Iraq wars represents a significant medical concern for troops and veterans. To better understand the consequences of primary-blast injury in humans, we present a case of a Marine exposed to multiple primary blasts during his 14-year military career. The neuropsychological profile of this formerly high-functioning veteran suggested primarily executive dysfunction. Diffusion-tensor imaging revealed white-matter pathology in long fiber tracks compared with a composite fractional-anisotropy template derived from a veteran reference control group without TBI. This study supports the existence of primary blast-induced neurotrauma in humans and introduces a neuroimaging technique with potential to discriminate multiple-blast TBI.
Duke Scholars
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- Neuropsychological Tests
- Middle Aged
- Male
- Magnetic Resonance Imaging
- Humans
- Frontal Lobe
- Female
- Experimental Psychology
- Diffusion Tensor Imaging
- Cognition Disorders
Citation
Published In
DOI
EISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Neuropsychological Tests
- Middle Aged
- Male
- Magnetic Resonance Imaging
- Humans
- Frontal Lobe
- Female
- Experimental Psychology
- Diffusion Tensor Imaging
- Cognition Disorders