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ALASKA: A Mathematica package for two-state kinetic analysis of protein folding reactions

Publication ,  Journal Article
Burton, RE; Busby, RS; Oas, TG
Published in: Journal of Biomolecular NMR
January 1, 1998

A Mathematica package (ALASKA) has been developed to simplify the measurement of protein folding kinetics by analysis of 1H NMR lineshape analysis. This package reads NMR data in ASCII format and can simulate an aromatic 1 NMR spectrum with or without lineshape broadening from chemical exchange. We describe the analysis of a urea denaturation series of a fast-folding protein, the G46A/G48A variant of monomeric λ repressor.

Duke Scholars

Published In

Journal of Biomolecular NMR

DOI

ISSN

0925-2738

Publication Date

January 1, 1998

Volume

11

Issue

3

Start / End Page

355 / 360

Related Subject Headings

  • Biophysics
  • 51 Physical sciences
  • 34 Chemical sciences
  • 31 Biological sciences
  • 06 Biological Sciences
  • 03 Chemical Sciences
  • 02 Physical Sciences
 

Citation

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Burton, R. E., Busby, R. S., & Oas, T. G. (1998). ALASKA: A Mathematica package for two-state kinetic analysis of protein folding reactions. Journal of Biomolecular NMR, 11(3), 355–360. https://doi.org/10.1023/a:1008276703114
Burton, R. E., R. S. Busby, and T. G. Oas. “ALASKA: A Mathematica package for two-state kinetic analysis of protein folding reactions.” Journal of Biomolecular NMR 11, no. 3 (January 1, 1998): 355–60. https://doi.org/10.1023/a:1008276703114.
Burton RE, Busby RS, Oas TG. ALASKA: A Mathematica package for two-state kinetic analysis of protein folding reactions. Journal of Biomolecular NMR. 1998 Jan 1;11(3):355–60.
Burton, R. E., et al. “ALASKA: A Mathematica package for two-state kinetic analysis of protein folding reactions.” Journal of Biomolecular NMR, vol. 11, no. 3, Jan. 1998, pp. 355–60. Scopus, doi:10.1023/a:1008276703114.
Burton RE, Busby RS, Oas TG. ALASKA: A Mathematica package for two-state kinetic analysis of protein folding reactions. Journal of Biomolecular NMR. 1998 Jan 1;11(3):355–360.
Journal cover image

Published In

Journal of Biomolecular NMR

DOI

ISSN

0925-2738

Publication Date

January 1, 1998

Volume

11

Issue

3

Start / End Page

355 / 360

Related Subject Headings

  • Biophysics
  • 51 Physical sciences
  • 34 Chemical sciences
  • 31 Biological sciences
  • 06 Biological Sciences
  • 03 Chemical Sciences
  • 02 Physical Sciences