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Feasibility of breast duct lavage performed by a physician extender.

Publication ,  Journal Article
Redlich, PN; Purdy, AC; Shidham, VB; Yun, HJ; Walker, A; Ota, D
Published in: Surgery
November 2004

BACKGROUND: The safety and feasibility of ductal lavage (DL), a risk-assessment tool utilizing a minimally invasive technique that permits sampling of breast duct epithelium, performed primarily by a nurse practitioner (NP), was studied prospectively. METHODS: Women at high risk for breast cancer with a normal clinical breast exam and mammogram were enrolled. Nipple aspirate fluid (NAF)-yielding ducts were identified, cannulated, and lavaged primarily by an NP in collaboration with a breast surgeon. Samples with sufficient cellularity were categorized as benign, mild atypia, marked atypia, or malignant. Pain and adverse events were recorded. RESULTS: Thirty-seven women, with a mean age of 51.7 years, were enrolled. Thirty-one (83.8%) women yielded NAF and, of those, 28 (90.3%) had one or more ducts successfully cannulated. Of 65 lavaged ducts in these 28 women, cellularity was adequate for diagnosis in 44 (67.7%) samples. Cytologic findings were as follows: 24 benign, 15 mild atypia, 4 marked atypia, and 1 malignant. The procedure was well tolerated with a mean pain score of 3.2 (SD +/- 1.81). The most frequent adverse event was breast fullness, reported by 44.8% of the women. Two women with marked atypia were evaluated further and found to have intraductal papillomata. The woman with malignant cytology had ductal carcinoma in situ. CONCLUSION: DL is a safe, generally well-tolerated procedure that can be performed successfully by a trained NP.

Duke Scholars

Published In

Surgery

DOI

ISSN

0039-6060

Publication Date

November 2004

Volume

136

Issue

5

Start / End Page

1077 / 1080

Location

United States

Related Subject Headings

  • Therapeutic Irrigation
  • Surgery
  • Patient Satisfaction
  • Nurse Practitioners
  • Nipples
  • Middle Aged
  • Humans
  • Genes, BRCA2
  • Genes, BRCA1
  • Female
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Redlich, P. N., Purdy, A. C., Shidham, V. B., Yun, H. J., Walker, A., & Ota, D. (2004). Feasibility of breast duct lavage performed by a physician extender. Surgery, 136(5), 1077–1080. https://doi.org/10.1016/j.surg.2004.08.004
Redlich, Philip N., Anna C. Purdy, Vinod B. Shidham, Hyun J. Yun, Alonzo Walker, and David Ota. “Feasibility of breast duct lavage performed by a physician extender.Surgery 136, no. 5 (November 2004): 1077–80. https://doi.org/10.1016/j.surg.2004.08.004.
Redlich PN, Purdy AC, Shidham VB, Yun HJ, Walker A, Ota D. Feasibility of breast duct lavage performed by a physician extender. Surgery. 2004 Nov;136(5):1077–80.
Redlich, Philip N., et al. “Feasibility of breast duct lavage performed by a physician extender.Surgery, vol. 136, no. 5, Nov. 2004, pp. 1077–80. Pubmed, doi:10.1016/j.surg.2004.08.004.
Redlich PN, Purdy AC, Shidham VB, Yun HJ, Walker A, Ota D. Feasibility of breast duct lavage performed by a physician extender. Surgery. 2004 Nov;136(5):1077–1080.
Journal cover image

Published In

Surgery

DOI

ISSN

0039-6060

Publication Date

November 2004

Volume

136

Issue

5

Start / End Page

1077 / 1080

Location

United States

Related Subject Headings

  • Therapeutic Irrigation
  • Surgery
  • Patient Satisfaction
  • Nurse Practitioners
  • Nipples
  • Middle Aged
  • Humans
  • Genes, BRCA2
  • Genes, BRCA1
  • Female