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Comparison of altitude effect on Mycobacterium tuberculosis infection between rural and urban communities in Peru.

Publication ,  Journal Article
Saito, M; Pan, WK; Gilman, RH; Bautista, CT; Bamrah, S; Martín, CA; Tsiouris, SJ; Argüello, DF; Martinez-Carrasco, G
Published in: The American journal of tropical medicine and hygiene
July 2006

The mechanism of high altitude effect on tuberculosis (TB) infection has not been fully established. We previously reported a lower positive tuberculin skin test (TST) prevalence in high altitude villages compared with sea level communities in Peru. In this study, four additional communities were tested to assess whether decreased TB transmission was also in urban environments at high altitude. TST results from 3,629 individuals in nine communities were analyzed using generalized estimating equations to account for community clustering. Positive TST prevalence was not significantly different between the urban highland and the urban non-highland communities after adjusting for age, household contacts with a TST-positive person or a TB case, and presence of a Bacillus Calmette-Guérin vaccination scar. The effect of population concentration and increased contact with active TB overwhelmed the protective effect of altitude in urban highlands. Highland cities require the same preventive efforts against TB as non-highland communities.

Duke Scholars

Published In

The American journal of tropical medicine and hygiene

DOI

EISSN

1476-1645

ISSN

0002-9637

Publication Date

July 2006

Volume

75

Issue

1

Start / End Page

49 / 54

Related Subject Headings

  • Urban Population
  • Tuberculosis
  • Tuberculin Test
  • Tropical Medicine
  • Sex Factors
  • Rural Population
  • Risk Factors
  • Prevalence
  • Peru
  • Mycobacterium tuberculosis
 

Citation

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Chicago
ICMJE
MLA
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Saito, M., Pan, W. K., Gilman, R. H., Bautista, C. T., Bamrah, S., Martín, C. A., … Martinez-Carrasco, G. (2006). Comparison of altitude effect on Mycobacterium tuberculosis infection between rural and urban communities in Peru. The American Journal of Tropical Medicine and Hygiene, 75(1), 49–54. https://doi.org/10.4269/ajtmh.2006.75.49
Saito, Mayuko, William K. Pan, Robert H. Gilman, Christian T. Bautista, Sapna Bamrah, Christopher A. Martín, Simon J. Tsiouris, D Fermín Argüello, and Gabriela Martinez-Carrasco. “Comparison of altitude effect on Mycobacterium tuberculosis infection between rural and urban communities in Peru.The American Journal of Tropical Medicine and Hygiene 75, no. 1 (July 2006): 49–54. https://doi.org/10.4269/ajtmh.2006.75.49.
Saito M, Pan WK, Gilman RH, Bautista CT, Bamrah S, Martín CA, et al. Comparison of altitude effect on Mycobacterium tuberculosis infection between rural and urban communities in Peru. The American journal of tropical medicine and hygiene. 2006 Jul;75(1):49–54.
Saito, Mayuko, et al. “Comparison of altitude effect on Mycobacterium tuberculosis infection between rural and urban communities in Peru.The American Journal of Tropical Medicine and Hygiene, vol. 75, no. 1, July 2006, pp. 49–54. Epmc, doi:10.4269/ajtmh.2006.75.49.
Saito M, Pan WK, Gilman RH, Bautista CT, Bamrah S, Martín CA, Tsiouris SJ, Argüello DF, Martinez-Carrasco G. Comparison of altitude effect on Mycobacterium tuberculosis infection between rural and urban communities in Peru. The American journal of tropical medicine and hygiene. 2006 Jul;75(1):49–54.

Published In

The American journal of tropical medicine and hygiene

DOI

EISSN

1476-1645

ISSN

0002-9637

Publication Date

July 2006

Volume

75

Issue

1

Start / End Page

49 / 54

Related Subject Headings

  • Urban Population
  • Tuberculosis
  • Tuberculin Test
  • Tropical Medicine
  • Sex Factors
  • Rural Population
  • Risk Factors
  • Prevalence
  • Peru
  • Mycobacterium tuberculosis