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Disseminated zygomycosis: report of four cases and review.

Publication ,  Journal Article
Ingram, CW; Sennesh, J; Cooper, JN; Perfect, JR
Published in: Rev Infect Dis
1989

We present four cases of disseminated zygomycosis that illustrate the characteristic clinical syndromes and natural history of this infection. The zygomycetes affect individuals immunosuppressed by age, drug therapy, or underlying disease. A previous splenectomy or deferoxamine therapy may be an additional factor in the development of disseminated zygomycosis. Clinical syndromes reflect vascular invasion and organ infarction. Diagnosis requires consideration of risk factors followed by biopsy of the affected organ for culture and for demonstration of broad nonseptate hyphae in tissue sections. Despite advances in the management of many bacterial and fungal infections in the immunosuppressed host, the results of therapy for disseminated zygomycosis remain dismal.

Duke Scholars

Published In

Rev Infect Dis

DOI

ISSN

0162-0886

Publication Date

1989

Volume

11

Issue

5

Start / End Page

741 / 754

Location

United States

Related Subject Headings

  • Virginia
  • Risk Factors
  • Neoplasms
  • Mucormycosis
  • Middle Aged
  • Male
  • Kidney Diseases
  • Immune Tolerance
  • Humans
  • Gastrointestinal Diseases
 

Citation

APA
Chicago
ICMJE
MLA
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Ingram, C. W., Sennesh, J., Cooper, J. N., & Perfect, J. R. (1989). Disseminated zygomycosis: report of four cases and review. Rev Infect Dis, 11(5), 741–754. https://doi.org/10.1093/clinids/11.5.741
Ingram, C. W., J. Sennesh, J. N. Cooper, and J. R. Perfect. “Disseminated zygomycosis: report of four cases and review.Rev Infect Dis 11, no. 5 (1989): 741–54. https://doi.org/10.1093/clinids/11.5.741.
Ingram CW, Sennesh J, Cooper JN, Perfect JR. Disseminated zygomycosis: report of four cases and review. Rev Infect Dis. 1989;11(5):741–54.
Ingram, C. W., et al. “Disseminated zygomycosis: report of four cases and review.Rev Infect Dis, vol. 11, no. 5, 1989, pp. 741–54. Pubmed, doi:10.1093/clinids/11.5.741.
Ingram CW, Sennesh J, Cooper JN, Perfect JR. Disseminated zygomycosis: report of four cases and review. Rev Infect Dis. 1989;11(5):741–754.

Published In

Rev Infect Dis

DOI

ISSN

0162-0886

Publication Date

1989

Volume

11

Issue

5

Start / End Page

741 / 754

Location

United States

Related Subject Headings

  • Virginia
  • Risk Factors
  • Neoplasms
  • Mucormycosis
  • Middle Aged
  • Male
  • Kidney Diseases
  • Immune Tolerance
  • Humans
  • Gastrointestinal Diseases