Haploidization in Saccharomyces cerevisiae induced by a deficiency in homologous recombination.
Publication
, Journal Article
Song, W; Petes, TD
Published in: Genetics
May 2012
Diploid Saccharomyes cerevisae strains lacking the RAD52 gene required for homologous recombination have a very high rate of chromosome loss. Two of four isolates subcultured ∼20 times (∼500 cell divisions) became haploid. These strains were capable of mating with wild-type haploids to produce diploid progeny capable of undergoing meiosis to produce four viable spores.
Duke Scholars
Published In
Genetics
DOI
EISSN
1943-2631
Publication Date
May 2012
Volume
191
Issue
1
Start / End Page
279 / 284
Location
United States
Related Subject Headings
- Saccharomyces cerevisiae Proteins
- Saccharomyces cerevisiae
- Rad52 DNA Repair and Recombination Protein
- Polymorphism, Single Nucleotide
- Oligonucleotide Array Sequence Analysis
- Homologous Recombination
- Haploidy
- Gene Deletion
- Developmental Biology
- Chromosomes, Fungal
Citation
APA
Chicago
ICMJE
MLA
NLM
Song, W., & Petes, T. D. (2012). Haploidization in Saccharomyces cerevisiae induced by a deficiency in homologous recombination. Genetics, 191(1), 279–284. https://doi.org/10.1534/genetics.111.138180
Song, Wei, and Thomas D. Petes. “Haploidization in Saccharomyces cerevisiae induced by a deficiency in homologous recombination.” Genetics 191, no. 1 (May 2012): 279–84. https://doi.org/10.1534/genetics.111.138180.
Song W, Petes TD. Haploidization in Saccharomyces cerevisiae induced by a deficiency in homologous recombination. Genetics. 2012 May;191(1):279–84.
Song, Wei, and Thomas D. Petes. “Haploidization in Saccharomyces cerevisiae induced by a deficiency in homologous recombination.” Genetics, vol. 191, no. 1, May 2012, pp. 279–84. Pubmed, doi:10.1534/genetics.111.138180.
Song W, Petes TD. Haploidization in Saccharomyces cerevisiae induced by a deficiency in homologous recombination. Genetics. 2012 May;191(1):279–284.
Published In
Genetics
DOI
EISSN
1943-2631
Publication Date
May 2012
Volume
191
Issue
1
Start / End Page
279 / 284
Location
United States
Related Subject Headings
- Saccharomyces cerevisiae Proteins
- Saccharomyces cerevisiae
- Rad52 DNA Repair and Recombination Protein
- Polymorphism, Single Nucleotide
- Oligonucleotide Array Sequence Analysis
- Homologous Recombination
- Haploidy
- Gene Deletion
- Developmental Biology
- Chromosomes, Fungal