Competition between adjacent meiotic recombination hotspots in the yeast Saccharomyces cerevisiae.
Publication
, Journal Article
Fan, QQ; Xu, F; White, MA; Petes, TD
Published in: Genetics
March 1997
In a wild-type strain of Saccharomyces cerevisiae, a hotspot for meiotic recombination is located upstream of the HIS4 gene. An insertion of a 49-bp telomeric sequence into the coding region of HIS4 strongly stimulates meiotic recombination and the local formation of meiosis-specific double-strand DNA breaks (DSBs). When strains are constructed in which both hotspots are heterozygous, hotspot activity is substantially less when the hotspots are on the same chromosome than when they are on opposite chromosomes.
Duke Scholars
Published In
Genetics
DOI
ISSN
0016-6731
Publication Date
March 1997
Volume
145
Issue
3
Start / End Page
661 / 670
Location
United States
Related Subject Headings
- Transcription Factors
- Telomere
- Saccharomyces cerevisiae Proteins
- Saccharomyces cerevisiae
- Recombination, Genetic
- Pyrophosphatases
- Meiosis
- Heterozygote
- Fungal Proteins
- Developmental Biology
Citation
APA
Chicago
ICMJE
MLA
NLM
Fan, Q. Q., Xu, F., White, M. A., & Petes, T. D. (1997). Competition between adjacent meiotic recombination hotspots in the yeast Saccharomyces cerevisiae. Genetics, 145(3), 661–670. https://doi.org/10.1093/genetics/145.3.661
Fan, Q. Q., F. Xu, M. A. White, and T. D. Petes. “Competition between adjacent meiotic recombination hotspots in the yeast Saccharomyces cerevisiae.” Genetics 145, no. 3 (March 1997): 661–70. https://doi.org/10.1093/genetics/145.3.661.
Fan QQ, Xu F, White MA, Petes TD. Competition between adjacent meiotic recombination hotspots in the yeast Saccharomyces cerevisiae. Genetics. 1997 Mar;145(3):661–70.
Fan, Q. Q., et al. “Competition between adjacent meiotic recombination hotspots in the yeast Saccharomyces cerevisiae.” Genetics, vol. 145, no. 3, Mar. 1997, pp. 661–70. Pubmed, doi:10.1093/genetics/145.3.661.
Fan QQ, Xu F, White MA, Petes TD. Competition between adjacent meiotic recombination hotspots in the yeast Saccharomyces cerevisiae. Genetics. 1997 Mar;145(3):661–670.
Published In
Genetics
DOI
ISSN
0016-6731
Publication Date
March 1997
Volume
145
Issue
3
Start / End Page
661 / 670
Location
United States
Related Subject Headings
- Transcription Factors
- Telomere
- Saccharomyces cerevisiae Proteins
- Saccharomyces cerevisiae
- Recombination, Genetic
- Pyrophosphatases
- Meiosis
- Heterozygote
- Fungal Proteins
- Developmental Biology