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Competition between adjacent meiotic recombination hotspots in the yeast Saccharomyces cerevisiae.

Publication ,  Journal Article
Fan, QQ; Xu, F; White, MA; Petes, TD
Published in: Genetics
March 1997

In a wild-type strain of Saccharomyces cerevisiae, a hotspot for meiotic recombination is located upstream of the HIS4 gene. An insertion of a 49-bp telomeric sequence into the coding region of HIS4 strongly stimulates meiotic recombination and the local formation of meiosis-specific double-strand DNA breaks (DSBs). When strains are constructed in which both hotspots are heterozygous, hotspot activity is substantially less when the hotspots are on the same chromosome than when they are on opposite chromosomes.

Duke Scholars

Published In

Genetics

DOI

ISSN

0016-6731

Publication Date

March 1997

Volume

145

Issue

3

Start / End Page

661 / 670

Location

United States

Related Subject Headings

  • Transcription Factors
  • Telomere
  • Saccharomyces cerevisiae Proteins
  • Saccharomyces cerevisiae
  • Recombination, Genetic
  • Pyrophosphatases
  • Meiosis
  • Heterozygote
  • Fungal Proteins
  • Developmental Biology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Fan, Q. Q., Xu, F., White, M. A., & Petes, T. D. (1997). Competition between adjacent meiotic recombination hotspots in the yeast Saccharomyces cerevisiae. Genetics, 145(3), 661–670. https://doi.org/10.1093/genetics/145.3.661
Fan, Q. Q., F. Xu, M. A. White, and T. D. Petes. “Competition between adjacent meiotic recombination hotspots in the yeast Saccharomyces cerevisiae.Genetics 145, no. 3 (March 1997): 661–70. https://doi.org/10.1093/genetics/145.3.661.
Fan QQ, Xu F, White MA, Petes TD. Competition between adjacent meiotic recombination hotspots in the yeast Saccharomyces cerevisiae. Genetics. 1997 Mar;145(3):661–70.
Fan, Q. Q., et al. “Competition between adjacent meiotic recombination hotspots in the yeast Saccharomyces cerevisiae.Genetics, vol. 145, no. 3, Mar. 1997, pp. 661–70. Pubmed, doi:10.1093/genetics/145.3.661.
Fan QQ, Xu F, White MA, Petes TD. Competition between adjacent meiotic recombination hotspots in the yeast Saccharomyces cerevisiae. Genetics. 1997 Mar;145(3):661–670.

Published In

Genetics

DOI

ISSN

0016-6731

Publication Date

March 1997

Volume

145

Issue

3

Start / End Page

661 / 670

Location

United States

Related Subject Headings

  • Transcription Factors
  • Telomere
  • Saccharomyces cerevisiae Proteins
  • Saccharomyces cerevisiae
  • Recombination, Genetic
  • Pyrophosphatases
  • Meiosis
  • Heterozygote
  • Fungal Proteins
  • Developmental Biology