TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene.
Publication
, Journal Article
Greenwell, PW; Kronmal, SL; Porter, SE; Gassenhuber, J; Obermaier, B; Petes, TD
Published in: Cell
September 8, 1995
Yeast chromosomes terminate in tracts of simple repetitive DNA (poly[G1-3T]). Mutations in the gene TEL1 result in shortened telomeres. Sequence analysis of TEL1 indicates that it encodes a very large (322 kDa) protein with amino acid motifs found in phosphatidylinositol/protein kinases. The closest homolog to TEL1 is the human ataxia telangiectasia gene.
Duke Scholars
Altmetric Attention Stats
Dimensions Citation Stats
Published In
Cell
DOI
ISSN
0092-8674
Publication Date
September 8, 1995
Volume
82
Issue
5
Start / End Page
823 / 829
Location
United States
Related Subject Headings
- Telomere
- Sequence Homology, Amino Acid
- Saccharomyces cerevisiae
- Mutation
- Molecular Sequence Data
- Mitosis
- Humans
- Genes, Fungal
- Developmental Biology
- Cloning, Molecular
Citation
APA
Chicago
ICMJE
MLA
NLM
Greenwell, P. W., Kronmal, S. L., Porter, S. E., Gassenhuber, J., Obermaier, B., & Petes, T. D. (1995). TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene. Cell, 82(5), 823–829. https://doi.org/10.1016/0092-8674(95)90479-4
Greenwell, P. W., S. L. Kronmal, S. E. Porter, J. Gassenhuber, B. Obermaier, and T. D. Petes. “TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene.” Cell 82, no. 5 (September 8, 1995): 823–29. https://doi.org/10.1016/0092-8674(95)90479-4.
Greenwell PW, Kronmal SL, Porter SE, Gassenhuber J, Obermaier B, Petes TD. TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene. Cell. 1995 Sep 8;82(5):823–9.
Greenwell, P. W., et al. “TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene.” Cell, vol. 82, no. 5, Sept. 1995, pp. 823–29. Pubmed, doi:10.1016/0092-8674(95)90479-4.
Greenwell PW, Kronmal SL, Porter SE, Gassenhuber J, Obermaier B, Petes TD. TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene. Cell. 1995 Sep 8;82(5):823–829.
Published In
Cell
DOI
ISSN
0092-8674
Publication Date
September 8, 1995
Volume
82
Issue
5
Start / End Page
823 / 829
Location
United States
Related Subject Headings
- Telomere
- Sequence Homology, Amino Acid
- Saccharomyces cerevisiae
- Mutation
- Molecular Sequence Data
- Mitosis
- Humans
- Genes, Fungal
- Developmental Biology
- Cloning, Molecular