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Genetic analysis of a meiotic recombination hotspot on chromosome III of Saccharomyces cerevisiae.

Publication ,  Journal Article
Symington, LS; Brown, A; Oliver, SG; Greenwell, P; Petes, TD
Published in: Genetics
August 1991

In a previous study, we analyzed meiotic recombination events that occurred in the 22-kb region (LEU2 to CEN3) of chromosome III of Saccharomyces cerevisiae. We found one region with an enhanced level of crossovers (a hotspot) and one region with a depressed level of crossovers. In this study, we show that about one-third of the crossovers that occur between LEU2 and CEN3 are initiated in a 1.3-kb region located approximately 6 kb from the centromere. Both crossovers and gene conversion events are initiated at this site. Events initiated at this position can be resolved as crossovers in regions located either centromere-distally or centromere-proximally from the initiation site.

Duke Scholars

Published In

Genetics

DOI

ISSN

0016-6731

Publication Date

August 1991

Volume

128

Issue

4

Start / End Page

717 / 727

Location

United States

Related Subject Headings

  • Saccharomyces cerevisiae
  • Recombination, Genetic
  • Molecular Sequence Data
  • Meiosis
  • Genetic Vectors
  • Genetic Markers
  • Gene Conversion
  • Developmental Biology
  • Crossing Over, Genetic
  • Chromosomes, Fungal
 

Citation

APA
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MLA
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Symington, L. S., Brown, A., Oliver, S. G., Greenwell, P., & Petes, T. D. (1991). Genetic analysis of a meiotic recombination hotspot on chromosome III of Saccharomyces cerevisiae. Genetics, 128(4), 717–727. https://doi.org/10.1093/genetics/128.4.717
Symington, L. S., A. Brown, S. G. Oliver, P. Greenwell, and T. D. Petes. “Genetic analysis of a meiotic recombination hotspot on chromosome III of Saccharomyces cerevisiae.Genetics 128, no. 4 (August 1991): 717–27. https://doi.org/10.1093/genetics/128.4.717.
Symington LS, Brown A, Oliver SG, Greenwell P, Petes TD. Genetic analysis of a meiotic recombination hotspot on chromosome III of Saccharomyces cerevisiae. Genetics. 1991 Aug;128(4):717–27.
Symington, L. S., et al. “Genetic analysis of a meiotic recombination hotspot on chromosome III of Saccharomyces cerevisiae.Genetics, vol. 128, no. 4, Aug. 1991, pp. 717–27. Pubmed, doi:10.1093/genetics/128.4.717.
Symington LS, Brown A, Oliver SG, Greenwell P, Petes TD. Genetic analysis of a meiotic recombination hotspot on chromosome III of Saccharomyces cerevisiae. Genetics. 1991 Aug;128(4):717–727.

Published In

Genetics

DOI

ISSN

0016-6731

Publication Date

August 1991

Volume

128

Issue

4

Start / End Page

717 / 727

Location

United States

Related Subject Headings

  • Saccharomyces cerevisiae
  • Recombination, Genetic
  • Molecular Sequence Data
  • Meiosis
  • Genetic Vectors
  • Genetic Markers
  • Gene Conversion
  • Developmental Biology
  • Crossing Over, Genetic
  • Chromosomes, Fungal