Cardiac regeneration.
Publication
, Journal Article
Choi, W-Y; Poss, KD
Published in: Curr Top Dev Biol
2012
The heart is a pump that is comprised of cardiac myocytes and other cell types and whose proper function is critical to quality of life. The ability to trigger regeneration of heart muscle following injury eludes adult mammals, a deficiency of great clinical impact. Major research efforts are attempting to change this through advances in cell therapy or activating endogenous regenerative mechanisms that exist only early in life. In contrast with mammals, lower vertebrates like zebrafish demonstrate an impressive natural capacity for cardiac regeneration throughout life. This review will cover recent progress in the field of heart regeneration with a focus on endogenous regenerative capacity and its potential manipulation.
Duke Scholars
Altmetric Attention Stats
Dimensions Citation Stats
Published In
Curr Top Dev Biol
DOI
EISSN
1557-8933
Publication Date
2012
Volume
100
Start / End Page
319 / 344
Location
United States
Related Subject Headings
- Regeneration
- Humans
- Heart Injuries
- Heart
- Disease Models, Animal
- Developmental Biology
- Cell- and Tissue-Based Therapy
- Animals
- 3102 Bioinformatics and computational biology
- 1114 Paediatrics and Reproductive Medicine
Citation
APA
Chicago
ICMJE
MLA
NLM
Choi, W.-Y., & Poss, K. D. (2012). Cardiac regeneration. Curr Top Dev Biol, 100, 319–344. https://doi.org/10.1016/B978-0-12-387786-4.00010-5
Choi, Wen-Yee, and Kenneth D. Poss. “Cardiac regeneration.” Curr Top Dev Biol 100 (2012): 319–44. https://doi.org/10.1016/B978-0-12-387786-4.00010-5.
Choi W-Y, Poss KD. Cardiac regeneration. Curr Top Dev Biol. 2012;100:319–44.
Choi, Wen-Yee, and Kenneth D. Poss. “Cardiac regeneration.” Curr Top Dev Biol, vol. 100, 2012, pp. 319–44. Pubmed, doi:10.1016/B978-0-12-387786-4.00010-5.
Choi W-Y, Poss KD. Cardiac regeneration. Curr Top Dev Biol. 2012;100:319–344.
Published In
Curr Top Dev Biol
DOI
EISSN
1557-8933
Publication Date
2012
Volume
100
Start / End Page
319 / 344
Location
United States
Related Subject Headings
- Regeneration
- Humans
- Heart Injuries
- Heart
- Disease Models, Animal
- Developmental Biology
- Cell- and Tissue-Based Therapy
- Animals
- 3102 Bioinformatics and computational biology
- 1114 Paediatrics and Reproductive Medicine