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Construction of modular circuits in the mammalian brain.

Publication ,  Journal Article
Purves, D; LaMantia, AS
Published in: Cold Spring Harbor symposia on quantitative biology
January 1990

Comparison of seemingly different modular units in the mammalian brain raises the possibility of a common mechanism for their formation: the growth of neuropil mediated by trophic interactions. The ongoing postnatal construction of modular circuits according to trophic interplay may in turn account for the remarkable plasticity of the juvenile brain. By the same token, the normal waning of circuit construction during postnatal development may explain the end of critical periods, the diminished ability to recover from injury in older animals, and the decline with increasing age in the ability of mammals to learn complex skills.

Duke Scholars

Published In

Cold Spring Harbor symposia on quantitative biology

DOI

EISSN

1943-4456

ISSN

0091-7451

Publication Date

January 1990

Volume

55

Start / End Page

445 / 452

Related Subject Headings

  • Visual Cortex
  • Olfactory Bulb
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  • Male
  • Macaca mulatta
  • Brain
  • Animals
  • 3101 Biochemistry and cell biology
  • 0601 Biochemistry and Cell Biology
 

Citation

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Purves, D., & LaMantia, A. S. (1990). Construction of modular circuits in the mammalian brain. Cold Spring Harbor Symposia on Quantitative Biology, 55, 445–452. https://doi.org/10.1101/sqb.1990.055.01.044
Purves, D., and A. S. LaMantia. “Construction of modular circuits in the mammalian brain.Cold Spring Harbor Symposia on Quantitative Biology 55 (January 1990): 445–52. https://doi.org/10.1101/sqb.1990.055.01.044.
Purves D, LaMantia AS. Construction of modular circuits in the mammalian brain. Cold Spring Harbor symposia on quantitative biology. 1990 Jan;55:445–52.
Purves, D., and A. S. LaMantia. “Construction of modular circuits in the mammalian brain.Cold Spring Harbor Symposia on Quantitative Biology, vol. 55, Jan. 1990, pp. 445–52. Epmc, doi:10.1101/sqb.1990.055.01.044.
Purves D, LaMantia AS. Construction of modular circuits in the mammalian brain. Cold Spring Harbor symposia on quantitative biology. 1990 Jan;55:445–452.

Published In

Cold Spring Harbor symposia on quantitative biology

DOI

EISSN

1943-4456

ISSN

0091-7451

Publication Date

January 1990

Volume

55

Start / End Page

445 / 452

Related Subject Headings

  • Visual Cortex
  • Olfactory Bulb
  • Mice
  • Male
  • Macaca mulatta
  • Brain
  • Animals
  • 3101 Biochemistry and cell biology
  • 0601 Biochemistry and Cell Biology