Thymoma followed by paroxysmal nocturnal hemoglobinuria: a unique clinical association in the context of multiorgan autoimmunity with a potential role for CD8+ T lymphocytes.
Publication
, Journal Article
Palmieri, G; Selleri, C; Montella, L; Bulgarelli, G; Vitiello, L; Merkabaoui, G; Ricci, P; Del Vecchio, L; Masci, A; Racioppi, L; Rotoli, B
Published in: Am J Hematol
October 2006
Seven years after a surgically resected thymoma, a female patient affected by myasthenia gravis and Good's syndrome presented with paroxysmal nocturnal hemoglobinuria (PNH). Co-culture experiments and spectratyping analyses indicated that CD8+ lymphocytes were involved in damaging hematopoietic precursors. While PNH clones have been identified in various hematological disorders, the sequential association of thymoma and PNH has been unreported so far.
Duke Scholars
Published In
Am J Hematol
DOI
ISSN
0361-8609
Publication Date
October 2006
Volume
81
Issue
10
Start / End Page
774 / 778
Location
United States
Related Subject Headings
- Thymus Neoplasms
- Thymoma
- Reverse Transcriptase Polymerase Chain Reaction
- Receptors, Antigen, T-Cell, alpha-beta
- Neoplasm Recurrence, Local
- Middle Aged
- Immunology
- Humans
- Hemoglobinuria, Paroxysmal
- Follow-Up Studies
Citation
APA
Chicago
ICMJE
MLA
NLM
Palmieri, G., Selleri, C., Montella, L., Bulgarelli, G., Vitiello, L., Merkabaoui, G., … Rotoli, B. (2006). Thymoma followed by paroxysmal nocturnal hemoglobinuria: a unique clinical association in the context of multiorgan autoimmunity with a potential role for CD8+ T lymphocytes. Am J Hematol, 81(10), 774–778. https://doi.org/10.1002/ajh.20699
Palmieri, Giovannella, Carmine Selleri, Liliana Montella, Goffredo Bulgarelli, Laura Vitiello, Ghassan Merkabaoui, Patrizia Ricci, et al. “Thymoma followed by paroxysmal nocturnal hemoglobinuria: a unique clinical association in the context of multiorgan autoimmunity with a potential role for CD8+ T lymphocytes.” Am J Hematol 81, no. 10 (October 2006): 774–78. https://doi.org/10.1002/ajh.20699.
Palmieri G, Selleri C, Montella L, Bulgarelli G, Vitiello L, Merkabaoui G, et al. Thymoma followed by paroxysmal nocturnal hemoglobinuria: a unique clinical association in the context of multiorgan autoimmunity with a potential role for CD8+ T lymphocytes. Am J Hematol. 2006 Oct;81(10):774–8.
Palmieri, Giovannella, et al. “Thymoma followed by paroxysmal nocturnal hemoglobinuria: a unique clinical association in the context of multiorgan autoimmunity with a potential role for CD8+ T lymphocytes.” Am J Hematol, vol. 81, no. 10, Oct. 2006, pp. 774–78. Pubmed, doi:10.1002/ajh.20699.
Palmieri G, Selleri C, Montella L, Bulgarelli G, Vitiello L, Merkabaoui G, Ricci P, Del Vecchio L, Masci A, Racioppi L, Rotoli B. Thymoma followed by paroxysmal nocturnal hemoglobinuria: a unique clinical association in the context of multiorgan autoimmunity with a potential role for CD8+ T lymphocytes. Am J Hematol. 2006 Oct;81(10):774–778.
Published In
Am J Hematol
DOI
ISSN
0361-8609
Publication Date
October 2006
Volume
81
Issue
10
Start / End Page
774 / 778
Location
United States
Related Subject Headings
- Thymus Neoplasms
- Thymoma
- Reverse Transcriptase Polymerase Chain Reaction
- Receptors, Antigen, T-Cell, alpha-beta
- Neoplasm Recurrence, Local
- Middle Aged
- Immunology
- Humans
- Hemoglobinuria, Paroxysmal
- Follow-Up Studies