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Partial splenectomy for hereditary spherocytosis.

Publication ,  Journal Article
Tracy, ET; Rice, HE
Published in: Pediatr Clin North Am
April 2008

The significant risks associated with total splenectomy have led to interest in the use of partial splenectomy as an alternative surgical therapy for children who have congenital hemolytic anemia. Partial splenectomy is designed to remove enough spleen to gain desired hematologic outcomes while preserving splenic immune function. Although preliminary data demonstrate successful laboratory and clinical outcomes after partial splenectomy in various congenital hemolytic anemias, conclusive data comparing the efficacy of partial splenectomy to total splenectomy are not reported. Based on preliminary data, a definitive clinical trial of partial splenectomy in children who have severe congenital hemolytic anemia may be warranted.

Duke Scholars

Published In

Pediatr Clin North Am

DOI

ISSN

0031-3955

Publication Date

April 2008

Volume

55

Issue

2

Start / End Page

503 / x

Location

United States

Related Subject Headings

  • Splenectomy
  • Spherocytosis, Hereditary
  • Postoperative Complications
  • Pediatrics
  • Humans
  • Child
  • 3213 Paediatrics
  • 1114 Paediatrics and Reproductive Medicine
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Tracy, E. T., & Rice, H. E. (2008). Partial splenectomy for hereditary spherocytosis. Pediatr Clin North Am, 55(2), 503–x. https://doi.org/10.1016/j.pcl.2008.02.001
Tracy, Elisabeth T., and Henry E. Rice. “Partial splenectomy for hereditary spherocytosis.Pediatr Clin North Am 55, no. 2 (April 2008): 503–x. https://doi.org/10.1016/j.pcl.2008.02.001.
Tracy ET, Rice HE. Partial splenectomy for hereditary spherocytosis. Pediatr Clin North Am. 2008 Apr;55(2):503–x.
Tracy, Elisabeth T., and Henry E. Rice. “Partial splenectomy for hereditary spherocytosis.Pediatr Clin North Am, vol. 55, no. 2, Apr. 2008, pp. 503–x. Pubmed, doi:10.1016/j.pcl.2008.02.001.
Tracy ET, Rice HE. Partial splenectomy for hereditary spherocytosis. Pediatr Clin North Am. 2008 Apr;55(2):503–x.
Journal cover image

Published In

Pediatr Clin North Am

DOI

ISSN

0031-3955

Publication Date

April 2008

Volume

55

Issue

2

Start / End Page

503 / x

Location

United States

Related Subject Headings

  • Splenectomy
  • Spherocytosis, Hereditary
  • Postoperative Complications
  • Pediatrics
  • Humans
  • Child
  • 3213 Paediatrics
  • 1114 Paediatrics and Reproductive Medicine