Partial splenectomy for hereditary spherocytosis.
Publication
, Journal Article
Tracy, ET; Rice, HE
Published in: Pediatr Clin North Am
April 2008
The significant risks associated with total splenectomy have led to interest in the use of partial splenectomy as an alternative surgical therapy for children who have congenital hemolytic anemia. Partial splenectomy is designed to remove enough spleen to gain desired hematologic outcomes while preserving splenic immune function. Although preliminary data demonstrate successful laboratory and clinical outcomes after partial splenectomy in various congenital hemolytic anemias, conclusive data comparing the efficacy of partial splenectomy to total splenectomy are not reported. Based on preliminary data, a definitive clinical trial of partial splenectomy in children who have severe congenital hemolytic anemia may be warranted.
Duke Scholars
Published In
Pediatr Clin North Am
DOI
ISSN
0031-3955
Publication Date
April 2008
Volume
55
Issue
2
Start / End Page
503 / x
Location
United States
Related Subject Headings
- Splenectomy
- Spherocytosis, Hereditary
- Postoperative Complications
- Pediatrics
- Humans
- Child
- 3213 Paediatrics
- 1114 Paediatrics and Reproductive Medicine
Citation
APA
Chicago
ICMJE
MLA
NLM
Tracy, E. T., & Rice, H. E. (2008). Partial splenectomy for hereditary spherocytosis. Pediatr Clin North Am, 55(2), 503–x. https://doi.org/10.1016/j.pcl.2008.02.001
Tracy, Elisabeth T., and Henry E. Rice. “Partial splenectomy for hereditary spherocytosis.” Pediatr Clin North Am 55, no. 2 (April 2008): 503–x. https://doi.org/10.1016/j.pcl.2008.02.001.
Tracy ET, Rice HE. Partial splenectomy for hereditary spherocytosis. Pediatr Clin North Am. 2008 Apr;55(2):503–x.
Tracy, Elisabeth T., and Henry E. Rice. “Partial splenectomy for hereditary spherocytosis.” Pediatr Clin North Am, vol. 55, no. 2, Apr. 2008, pp. 503–x. Pubmed, doi:10.1016/j.pcl.2008.02.001.
Tracy ET, Rice HE. Partial splenectomy for hereditary spherocytosis. Pediatr Clin North Am. 2008 Apr;55(2):503–x.
Published In
Pediatr Clin North Am
DOI
ISSN
0031-3955
Publication Date
April 2008
Volume
55
Issue
2
Start / End Page
503 / x
Location
United States
Related Subject Headings
- Splenectomy
- Spherocytosis, Hereditary
- Postoperative Complications
- Pediatrics
- Humans
- Child
- 3213 Paediatrics
- 1114 Paediatrics and Reproductive Medicine