WAVE signalling: from biochemistry to biology.
Publication
, Journal Article
Soderling, SH; Scott, JD
Published in: Biochem Soc Trans
February 2006
The small GTPases Rho, Rac and Cdc42 (cell-division cycle 42) function as molecular switches to modulate the actin cytoskeleton. They achieve this by modulating the activity of downstream cellular targets. One group of Rho GTPase effectors, WAVE (Wiskott-Aldrich syndrome protein verprolin homologous)-1, WAVE-2 and WAVE-3, function as scaffolds for actin-based signalling complexes. The present review highlights current knowledge regarding the biochemistry of the WAVE signalling complexes and their biological significance.
Duke Scholars
Published In
Biochem Soc Trans
DOI
ISSN
0300-5127
Publication Date
February 2006
Volume
34
Issue
Pt 1
Start / End Page
73 / 76
Location
England
Related Subject Headings
- Wiskott-Aldrich Syndrome Protein Family
- Signal Transduction
- Multiprotein Complexes
- Biochemistry & Molecular Biology
- Animals
- 3101 Biochemistry and cell biology
- 1101 Medical Biochemistry and Metabolomics
- 0601 Biochemistry and Cell Biology
Citation
APA
Chicago
ICMJE
MLA
NLM
Soderling, S. H., & Scott, J. D. (2006). WAVE signalling: from biochemistry to biology. Biochem Soc Trans, 34(Pt 1), 73–76. https://doi.org/10.1042/BST0340073
Soderling, S. H., and J. D. Scott. “WAVE signalling: from biochemistry to biology.” Biochem Soc Trans 34, no. Pt 1 (February 2006): 73–76. https://doi.org/10.1042/BST0340073.
Soderling SH, Scott JD. WAVE signalling: from biochemistry to biology. Biochem Soc Trans. 2006 Feb;34(Pt 1):73–6.
Soderling, S. H., and J. D. Scott. “WAVE signalling: from biochemistry to biology.” Biochem Soc Trans, vol. 34, no. Pt 1, Feb. 2006, pp. 73–76. Pubmed, doi:10.1042/BST0340073.
Soderling SH, Scott JD. WAVE signalling: from biochemistry to biology. Biochem Soc Trans. 2006 Feb;34(Pt 1):73–76.
Published In
Biochem Soc Trans
DOI
ISSN
0300-5127
Publication Date
February 2006
Volume
34
Issue
Pt 1
Start / End Page
73 / 76
Location
England
Related Subject Headings
- Wiskott-Aldrich Syndrome Protein Family
- Signal Transduction
- Multiprotein Complexes
- Biochemistry & Molecular Biology
- Animals
- 3101 Biochemistry and cell biology
- 1101 Medical Biochemistry and Metabolomics
- 0601 Biochemistry and Cell Biology