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WAVE signalling: from biochemistry to biology.

Publication ,  Journal Article
Soderling, SH; Scott, JD
Published in: Biochem Soc Trans
February 2006

The small GTPases Rho, Rac and Cdc42 (cell-division cycle 42) function as molecular switches to modulate the actin cytoskeleton. They achieve this by modulating the activity of downstream cellular targets. One group of Rho GTPase effectors, WAVE (Wiskott-Aldrich syndrome protein verprolin homologous)-1, WAVE-2 and WAVE-3, function as scaffolds for actin-based signalling complexes. The present review highlights current knowledge regarding the biochemistry of the WAVE signalling complexes and their biological significance.

Duke Scholars

Published In

Biochem Soc Trans

DOI

ISSN

0300-5127

Publication Date

February 2006

Volume

34

Issue

Pt 1

Start / End Page

73 / 76

Location

England

Related Subject Headings

  • Wiskott-Aldrich Syndrome Protein Family
  • Signal Transduction
  • Multiprotein Complexes
  • Biochemistry & Molecular Biology
  • Animals
  • 3101 Biochemistry and cell biology
  • 1101 Medical Biochemistry and Metabolomics
  • 0601 Biochemistry and Cell Biology
 

Citation

APA
Chicago
ICMJE
MLA
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Soderling, S. H., & Scott, J. D. (2006). WAVE signalling: from biochemistry to biology. Biochem Soc Trans, 34(Pt 1), 73–76. https://doi.org/10.1042/BST0340073
Soderling, S. H., and J. D. Scott. “WAVE signalling: from biochemistry to biology.Biochem Soc Trans 34, no. Pt 1 (February 2006): 73–76. https://doi.org/10.1042/BST0340073.
Soderling SH, Scott JD. WAVE signalling: from biochemistry to biology. Biochem Soc Trans. 2006 Feb;34(Pt 1):73–6.
Soderling, S. H., and J. D. Scott. “WAVE signalling: from biochemistry to biology.Biochem Soc Trans, vol. 34, no. Pt 1, Feb. 2006, pp. 73–76. Pubmed, doi:10.1042/BST0340073.
Soderling SH, Scott JD. WAVE signalling: from biochemistry to biology. Biochem Soc Trans. 2006 Feb;34(Pt 1):73–76.
Journal cover image

Published In

Biochem Soc Trans

DOI

ISSN

0300-5127

Publication Date

February 2006

Volume

34

Issue

Pt 1

Start / End Page

73 / 76

Location

England

Related Subject Headings

  • Wiskott-Aldrich Syndrome Protein Family
  • Signal Transduction
  • Multiprotein Complexes
  • Biochemistry & Molecular Biology
  • Animals
  • 3101 Biochemistry and cell biology
  • 1101 Medical Biochemistry and Metabolomics
  • 0601 Biochemistry and Cell Biology