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Current challenges in diagnosing and treating nontuberculous mycobacterial pulmonary disease

Publication ,  Journal Article
Gadkowski, LB; Stout, JE
Published in: Infections in Medicine
September 1, 2006

Patients with pulmonary disease caused by nontuberculous mycobacteria typically present with chronic cough and fatigue, sometimes with hemoptysis and weight loss as well. High-resolution CT is the most helpful radiographic study; it typically shows pulmonary nodules with adjacent bronchiectasis. Obtaining multiple sputum specimens for acid-fast staining and mycobacterial culture is an important part of the diagnostic workup. The diagnosis should be clearly established before treatment is initiated. Traditional regimens include isoniazid, rifampin, and ethambutol. More recent therapies include azithromycin, clarithromycin, rifabutin, and the newer fluoroquinolones. Surgical resection remains an option for patients with relatively localized disease who have a suboptimal response to medical therapy.

Duke Scholars

Published In

Infections in Medicine

ISSN

0749-6524

Publication Date

September 1, 2006

Volume

23

Issue

9

Start / End Page

425 / 433

Related Subject Headings

  • Microbiology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Gadkowski, L. B., & Stout, J. E. (2006). Current challenges in diagnosing and treating nontuberculous mycobacterial pulmonary disease. Infections in Medicine, 23(9), 425–433.
Gadkowski, L. B., and J. E. Stout. “Current challenges in diagnosing and treating nontuberculous mycobacterial pulmonary disease.” Infections in Medicine 23, no. 9 (September 1, 2006): 425–33.
Gadkowski LB, Stout JE. Current challenges in diagnosing and treating nontuberculous mycobacterial pulmonary disease. Infections in Medicine. 2006 Sep 1;23(9):425–33.
Gadkowski, L. B., and J. E. Stout. “Current challenges in diagnosing and treating nontuberculous mycobacterial pulmonary disease.” Infections in Medicine, vol. 23, no. 9, Sept. 2006, pp. 425–33.
Gadkowski LB, Stout JE. Current challenges in diagnosing and treating nontuberculous mycobacterial pulmonary disease. Infections in Medicine. 2006 Sep 1;23(9):425–433.

Published In

Infections in Medicine

ISSN

0749-6524

Publication Date

September 1, 2006

Volume

23

Issue

9

Start / End Page

425 / 433

Related Subject Headings

  • Microbiology