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Design and construction of an evanescent optical wave device for the recanalization of vessels

Publication ,  Journal Article
Hooper, BA; LaVerde, GC; Von Ramm, OT
Published in: Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
November 21, 2001

Removing atherosclerotic material without transecting the vessel wall is a common problem for vascular surgeons and interventional cardiologists. The goal of this project is to design and construct a device that uses evanescent optical waves for precise, controlled laser ablation. For laser light incident at an angle to an optic-tissue interface greater than or equal to the critical angle, an evanescent optical wave is launched into the tissue. With evanescent optical waves, there is no free-beam propagation and the laser energy can be confined to a layer less than one wavelength thick at the optic-tissue interface. Several device designs have been proposed and constructed. The Duke University Mark III Infrared Free-Electron Laser is used to study energy deposition and ablation mechanisms at sapphire-tissue and zinc sulfide-tissue interfaces. Ablation experiments on human low-density lipoprotein and aorta tissue are presented. © 2001 Elsevier Science B.V. All rights reserved.

Duke Scholars

Published In

Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

DOI

ISSN

0168-9002

Publication Date

November 21, 2001

Volume

475

Issue

1-3

Start / End Page

645 / 649

Related Subject Headings

  • Nuclear & Particles Physics
  • 5106 Nuclear and plasma physics
  • 0299 Other Physical Sciences
  • 0202 Atomic, Molecular, Nuclear, Particle and Plasma Physics
  • 0201 Astronomical and Space Sciences
 

Citation

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Hooper, B. A., LaVerde, G. C., & Von Ramm, O. T. (2001). Design and construction of an evanescent optical wave device for the recanalization of vessels. Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 475(1–3), 645–649. https://doi.org/10.1016/S0168-9002(01)01691-6
Hooper, B. A., G. C. LaVerde, and O. T. Von Ramm. “Design and construction of an evanescent optical wave device for the recanalization of vessels.” Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 475, no. 1–3 (November 21, 2001): 645–49. https://doi.org/10.1016/S0168-9002(01)01691-6.
Hooper BA, LaVerde GC, Von Ramm OT. Design and construction of an evanescent optical wave device for the recanalization of vessels. Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 2001 Nov 21;475(1–3):645–9.
Hooper, B. A., et al. “Design and construction of an evanescent optical wave device for the recanalization of vessels.” Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, vol. 475, no. 1–3, Nov. 2001, pp. 645–49. Scopus, doi:10.1016/S0168-9002(01)01691-6.
Hooper BA, LaVerde GC, Von Ramm OT. Design and construction of an evanescent optical wave device for the recanalization of vessels. Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 2001 Nov 21;475(1–3):645–649.
Journal cover image

Published In

Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

DOI

ISSN

0168-9002

Publication Date

November 21, 2001

Volume

475

Issue

1-3

Start / End Page

645 / 649

Related Subject Headings

  • Nuclear & Particles Physics
  • 5106 Nuclear and plasma physics
  • 0299 Other Physical Sciences
  • 0202 Atomic, Molecular, Nuclear, Particle and Plasma Physics
  • 0201 Astronomical and Space Sciences