White matter hyperintensity on magnetic resonance imaging: clinical and neuroanatomic correlates in the depressed elderly.
Publication
, Journal Article
Coffey, CE; Figiel, GS; Djang, WT; Saunders, WB; Weiner, RD
Published in: J Neuropsychiatry Clin Neurosci
1989
In a prospective study of depressed elderly patients referred for electroconvulsive therapy (ECT), subcortical white matter hyperintensity (WMH) was seen in all 51 patients 60 years or older who received magnetic resonance imaging (MRI) prior to treatment. In over half of the patients the WMH was formally rated as at least moderately severe, and it was commonly associated with other structural brain changes. The majority (80%) of patients had late-age-onset depression, suggesting that structural brain changes may interact with aging to facilitate the emergency of depression in late life.
Duke Scholars
Published In
J Neuropsychiatry Clin Neurosci
DOI
ISSN
0895-0172
Publication Date
1989
Volume
1
Issue
2
Start / End Page
135 / 144
Location
United States
Related Subject Headings
- Psychiatry
- Middle Aged
- Male
- Magnetic Resonance Imaging
- Humans
- Female
- Electroconvulsive Therapy
- Dominance, Cerebral
- Depressive Disorder
- Dementia
Citation
APA
Chicago
ICMJE
MLA
NLM
Coffey, C. E., Figiel, G. S., Djang, W. T., Saunders, W. B., & Weiner, R. D. (1989). White matter hyperintensity on magnetic resonance imaging: clinical and neuroanatomic correlates in the depressed elderly. J Neuropsychiatry Clin Neurosci, 1(2), 135–144. https://doi.org/10.1176/jnp.1.2.135
Coffey, C. E., G. S. Figiel, W. T. Djang, W. B. Saunders, and R. D. Weiner. “White matter hyperintensity on magnetic resonance imaging: clinical and neuroanatomic correlates in the depressed elderly.” J Neuropsychiatry Clin Neurosci 1, no. 2 (1989): 135–44. https://doi.org/10.1176/jnp.1.2.135.
Coffey CE, Figiel GS, Djang WT, Saunders WB, Weiner RD. White matter hyperintensity on magnetic resonance imaging: clinical and neuroanatomic correlates in the depressed elderly. J Neuropsychiatry Clin Neurosci. 1989;1(2):135–44.
Coffey, C. E., et al. “White matter hyperintensity on magnetic resonance imaging: clinical and neuroanatomic correlates in the depressed elderly.” J Neuropsychiatry Clin Neurosci, vol. 1, no. 2, 1989, pp. 135–44. Pubmed, doi:10.1176/jnp.1.2.135.
Coffey CE, Figiel GS, Djang WT, Saunders WB, Weiner RD. White matter hyperintensity on magnetic resonance imaging: clinical and neuroanatomic correlates in the depressed elderly. J Neuropsychiatry Clin Neurosci. 1989;1(2):135–144.
Published In
J Neuropsychiatry Clin Neurosci
DOI
ISSN
0895-0172
Publication Date
1989
Volume
1
Issue
2
Start / End Page
135 / 144
Location
United States
Related Subject Headings
- Psychiatry
- Middle Aged
- Male
- Magnetic Resonance Imaging
- Humans
- Female
- Electroconvulsive Therapy
- Dominance, Cerebral
- Depressive Disorder
- Dementia