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Regulated shuttling of the histone deacetylase HDAC5 to the nucleus may put a brake on cocaine addiction.

Publication ,  Journal Article
West, AE
Published in: Neuron
January 12, 2012
Published version (DOI) Link to item

The histone deacetylase HDAC5 has been shown to regulate behavioral adaptations to cocaine. In this issue of Neuron, Taniguchi et al. (2012) describe a cAMP-dependent signaling pathway that regulates nuclear accumulation of HDAC5, suggesting a mechanism to couple cocaine with changes in HDAC5 function.

Duke Scholars

Anne Elizabeth West
Author Anne Elizabeth West Neurobiology

Published In

Neuron

DOI

10.1016/j.neuron.2011.12.016

EISSN

1097-4199

Publication Date

January 12, 2012

Volume

73

Issue

1

Start / End Page

1 / 3

Location

United States

Related Subject Headings

  • Reward
  • Neurology & Neurosurgery
  • Male
  • Humans
  • Histone Deacetylases
  • Dopamine Uptake Inhibitors
  • Cyclic AMP
  • Cocaine
  • Animals
  • Active Transport, Cell Nucleus
 

Citation

APA
Chicago
ICMJE
MLA
NLM
West, A. E. (2012). Regulated shuttling of the histone deacetylase HDAC5 to the nucleus may put a brake on cocaine addiction. Neuron, 73(1), 1–3. https://doi.org/10.1016/j.neuron.2011.12.016
West, Anne E. “Regulated shuttling of the histone deacetylase HDAC5 to the nucleus may put a brake on cocaine addiction.” Neuron 73, no. 1 (January 12, 2012): 1–3. https://doi.org/10.1016/j.neuron.2011.12.016.
West, Anne E. “Regulated shuttling of the histone deacetylase HDAC5 to the nucleus may put a brake on cocaine addiction.” Neuron, vol. 73, no. 1, Jan. 2012, pp. 1–3. Pubmed, doi:10.1016/j.neuron.2011.12.016.
Journal cover image

Published In

Neuron

DOI

10.1016/j.neuron.2011.12.016

EISSN

1097-4199

Publication Date

January 12, 2012

Volume

73

Issue

1

Start / End Page

1 / 3

Location

United States

Related Subject Headings

  • Reward
  • Neurology & Neurosurgery
  • Male
  • Humans
  • Histone Deacetylases
  • Dopamine Uptake Inhibitors
  • Cyclic AMP
  • Cocaine
  • Animals
  • Active Transport, Cell Nucleus