Chemical stability of metallic nanoparticles: a parameter controlling their potential cellular toxicity in vitro.
Publication
, Journal Article
Auffan, M; Rose, J; Wiesner, MR; Bottero, J-Y
Published in: Environmental pollution (Barking, Essex : 1987)
April 2009
The level of production of nanoparticles will inevitably lead to their appearance in air, water, soils, and organisms. A theoretical framework that relates properties of nanoparticles to their biological effects is needed to identify possible risks to human health and the environment. This paper considers the properties of dispersed metallic nanoparticles and highlights the relationship between the chemical stability of these nanoparticles and their in vitro toxicity. Analysis of published data suggests that chemically stable metallic nanoparticles have no significant cellular toxicity, whereas nanoparticles able to be oxidized, reduced or dissolved are cytotoxic and even genotoxic for cellular organisms.
Duke Scholars
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Published In
Environmental pollution (Barking, Essex : 1987)
DOI
EISSN
1873-6424
ISSN
0269-7491
Publication Date
April 2009
Volume
157
Issue
4
Start / End Page
1127 / 1133
Related Subject Headings
- Solubility
- Oxidation-Reduction
- Mutagens
- Models, Chemical
- Metal Nanoparticles
- Humans
- Environmental Sciences
- Environmental Pollutants
- Ecotoxicology
- Cytotoxins
Citation
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Chicago
ICMJE
MLA
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Auffan, M., Rose, J., Wiesner, M. R., & Bottero, J.-Y. (2009). Chemical stability of metallic nanoparticles: a parameter controlling their potential cellular toxicity in vitro. Environmental Pollution (Barking, Essex : 1987), 157(4), 1127–1133. https://doi.org/10.1016/j.envpol.2008.10.002
Auffan, Mélanie, Jérôme Rose, Mark R. Wiesner, and Jean-Yves Bottero. “Chemical stability of metallic nanoparticles: a parameter controlling their potential cellular toxicity in vitro.” Environmental Pollution (Barking, Essex : 1987) 157, no. 4 (April 2009): 1127–33. https://doi.org/10.1016/j.envpol.2008.10.002.
Auffan M, Rose J, Wiesner MR, Bottero J-Y. Chemical stability of metallic nanoparticles: a parameter controlling their potential cellular toxicity in vitro. Environmental pollution (Barking, Essex : 1987). 2009 Apr;157(4):1127–33.
Auffan, Mélanie, et al. “Chemical stability of metallic nanoparticles: a parameter controlling their potential cellular toxicity in vitro.” Environmental Pollution (Barking, Essex : 1987), vol. 157, no. 4, Apr. 2009, pp. 1127–33. Epmc, doi:10.1016/j.envpol.2008.10.002.
Auffan M, Rose J, Wiesner MR, Bottero J-Y. Chemical stability of metallic nanoparticles: a parameter controlling their potential cellular toxicity in vitro. Environmental pollution (Barking, Essex : 1987). 2009 Apr;157(4):1127–1133.
Published In
Environmental pollution (Barking, Essex : 1987)
DOI
EISSN
1873-6424
ISSN
0269-7491
Publication Date
April 2009
Volume
157
Issue
4
Start / End Page
1127 / 1133
Related Subject Headings
- Solubility
- Oxidation-Reduction
- Mutagens
- Models, Chemical
- Metal Nanoparticles
- Humans
- Environmental Sciences
- Environmental Pollutants
- Ecotoxicology
- Cytotoxins