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Gold nanocages as contrast agents for spectroscopic optical coherence tomography.

Publication ,  Journal Article
Cang, H; Sun, T; Li, Z-Y; Chen, J; Wiley, BJ; Xia, Y; Li, X
Published in: Optics letters
November 2005

We describe gold nanocages as a new class of potential contrast agent for spectroscopic optical coherence tomography (OCT). Monodispersed gold nanocages of an approximately 35 nm edge length exhibit strong optical resonance, with the peak wavelength tunable in the near-infrared range. We characterized the optical properties of the nanocage by using OCT experiments along with numerical calculations, revealing an absorption cross section approximately 5 orders of magnitude larger than conventional dyes. Experiments with tissue phantoms demonstrated that the nanocages provide enhanced contrast for spectroscopic as well as conventional intensity-based OCT imaging.

Duke Scholars

Published In

Optics letters

DOI

EISSN

1539-4794

ISSN

0146-9592

Publication Date

November 2005

Volume

30

Issue

22

Start / End Page

3048 / 3050

Related Subject Headings

  • Tomography, Optical Coherence
  • Sensitivity and Specificity
  • Reproducibility of Results
  • Particle Size
  • Optics
  • Nanostructures
  • Image Enhancement
  • Contrast Media
  • 5102 Atomic, molecular and optical physics
  • 4009 Electronics, sensors and digital hardware
 

Citation

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Cang, H., Sun, T., Li, Z.-Y., Chen, J., Wiley, B. J., Xia, Y., & Li, X. (2005). Gold nanocages as contrast agents for spectroscopic optical coherence tomography. Optics Letters, 30(22), 3048–3050. https://doi.org/10.1364/ol.30.003048
Cang, Hu, Tao Sun, Zhi-Yuan Li, Jingyi Chen, Benjamin J. Wiley, Younan Xia, and Xingde Li. “Gold nanocages as contrast agents for spectroscopic optical coherence tomography.Optics Letters 30, no. 22 (November 2005): 3048–50. https://doi.org/10.1364/ol.30.003048.
Cang H, Sun T, Li Z-Y, Chen J, Wiley BJ, Xia Y, et al. Gold nanocages as contrast agents for spectroscopic optical coherence tomography. Optics letters. 2005 Nov;30(22):3048–50.
Cang, Hu, et al. “Gold nanocages as contrast agents for spectroscopic optical coherence tomography.Optics Letters, vol. 30, no. 22, Nov. 2005, pp. 3048–50. Epmc, doi:10.1364/ol.30.003048.
Cang H, Sun T, Li Z-Y, Chen J, Wiley BJ, Xia Y, Li X. Gold nanocages as contrast agents for spectroscopic optical coherence tomography. Optics letters. 2005 Nov;30(22):3048–3050.
Journal cover image

Published In

Optics letters

DOI

EISSN

1539-4794

ISSN

0146-9592

Publication Date

November 2005

Volume

30

Issue

22

Start / End Page

3048 / 3050

Related Subject Headings

  • Tomography, Optical Coherence
  • Sensitivity and Specificity
  • Reproducibility of Results
  • Particle Size
  • Optics
  • Nanostructures
  • Image Enhancement
  • Contrast Media
  • 5102 Atomic, molecular and optical physics
  • 4009 Electronics, sensors and digital hardware