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Effects of marijuana on performance of a computerized cognitive-neuromotor test battery.

Publication ,  Journal Article
Wilson, WH; Ellinwood, EH; Mathew, RJ; Johnson, K
Published in: Psychiatry Res
February 1994

To evaluate the sensitivity of a computerized cognitive-neuromotor test battery in assessing the effects of marijuana (delta-9-tetrahydrocannabinol [THC]), we conducted a study of 10 healthy male volunteers who were experienced marijuana smokers. After extensive training on the performance tasks, each subject was tested on three separate days after smoking a cigarette containing either 1.75% THC, 3.55% THC, or placebo according to a randomized double-blind repeated measures design. Testing was carried out before smoking and 30, 90, and 150 minutes after smoking the cigarette. Of the five tasks employed, the digit-symbol substitution test with memory and the reaction time task were the measures most sensitive to effects of marijuana. We examined the usefulness of the coefficient of variation and effect size as indices of sensitivity to be used across different types of tasks.

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Published In

Psychiatry Res

DOI

ISSN

0165-1781

Publication Date

February 1994

Volume

51

Issue

2

Start / End Page

115 / 125

Location

Ireland

Related Subject Headings

  • Task Performance and Analysis
  • Substance-Related Disorders
  • Self-Assessment
  • Reaction Time
  • Psychiatry
  • Motor Skills
  • Memory Disorders
  • Male
  • Humans
  • Heart Rate
 

Citation

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Wilson, W. H., Ellinwood, E. H., Mathew, R. J., & Johnson, K. (1994). Effects of marijuana on performance of a computerized cognitive-neuromotor test battery. Psychiatry Res, 51(2), 115–125. https://doi.org/10.1016/0165-1781(94)90031-0
Wilson, W. H., E. H. Ellinwood, R. J. Mathew, and K. Johnson. “Effects of marijuana on performance of a computerized cognitive-neuromotor test battery.Psychiatry Res 51, no. 2 (February 1994): 115–25. https://doi.org/10.1016/0165-1781(94)90031-0.
Wilson WH, Ellinwood EH, Mathew RJ, Johnson K. Effects of marijuana on performance of a computerized cognitive-neuromotor test battery. Psychiatry Res. 1994 Feb;51(2):115–25.
Wilson, W. H., et al. “Effects of marijuana on performance of a computerized cognitive-neuromotor test battery.Psychiatry Res, vol. 51, no. 2, Feb. 1994, pp. 115–25. Pubmed, doi:10.1016/0165-1781(94)90031-0.
Wilson WH, Ellinwood EH, Mathew RJ, Johnson K. Effects of marijuana on performance of a computerized cognitive-neuromotor test battery. Psychiatry Res. 1994 Feb;51(2):115–125.
Journal cover image

Published In

Psychiatry Res

DOI

ISSN

0165-1781

Publication Date

February 1994

Volume

51

Issue

2

Start / End Page

115 / 125

Location

Ireland

Related Subject Headings

  • Task Performance and Analysis
  • Substance-Related Disorders
  • Self-Assessment
  • Reaction Time
  • Psychiatry
  • Motor Skills
  • Memory Disorders
  • Male
  • Humans
  • Heart Rate