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Acute changes in cerebral blood flow after smoking marijuana.

Publication ,  Journal Article
Mathew, RJ; Wilson, WH
Published in: Life Sci
1993

In experienced marijuana smokers, marijuana smoking was accompanied by a significant bilateral increase in cerebral blood flow (CBF) especially in the frontal regions and cerebral blood velocity. The post-marijuana CBF increase could not be explained on the basis on changes in general circulation or respiration. Similarly, the CBF increase was unrelated to plasma levels of tetrahydrocannabinol and extracranial circulation. Behavioral changes showed significant correlations with CBF. CBF and brain function are closely coupled and therefore it seemed highly likely that CBF changes after marijuana were closely related to its effect on mood and behavior.

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Published In

Life Sci

DOI

ISSN

0024-3205

Publication Date

1993

Volume

52

Issue

8

Start / End Page

757 / 767

Location

Netherlands

Related Subject Headings

  • Statistics as Topic
  • Pharmacology & Pharmacy
  • Male
  • Humans
  • Female
  • Echoencephalography
  • Dronabinol
  • Cerebrovascular Circulation
  • Cannabis
  • Behavior
 

Citation

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Mathew, R. J., & Wilson, W. H. (1993). Acute changes in cerebral blood flow after smoking marijuana. Life Sci, 52(8), 757–767. https://doi.org/10.1016/0024-3205(93)90239-y
Mathew, R. J., and W. H. Wilson. “Acute changes in cerebral blood flow after smoking marijuana.Life Sci 52, no. 8 (1993): 757–67. https://doi.org/10.1016/0024-3205(93)90239-y.
Mathew RJ, Wilson WH. Acute changes in cerebral blood flow after smoking marijuana. Life Sci. 1993;52(8):757–67.
Mathew, R. J., and W. H. Wilson. “Acute changes in cerebral blood flow after smoking marijuana.Life Sci, vol. 52, no. 8, 1993, pp. 757–67. Pubmed, doi:10.1016/0024-3205(93)90239-y.
Mathew RJ, Wilson WH. Acute changes in cerebral blood flow after smoking marijuana. Life Sci. 1993;52(8):757–767.
Journal cover image

Published In

Life Sci

DOI

ISSN

0024-3205

Publication Date

1993

Volume

52

Issue

8

Start / End Page

757 / 767

Location

Netherlands

Related Subject Headings

  • Statistics as Topic
  • Pharmacology & Pharmacy
  • Male
  • Humans
  • Female
  • Echoencephalography
  • Dronabinol
  • Cerebrovascular Circulation
  • Cannabis
  • Behavior