Depersonalization after marijuana smoking.
Depersonalization and other behavioral and physiological indices were monitored before and after the administration of high- and low-potency marijuana cigarettes and a placebo cigarette in 35 physically and mentally healthy normal volunteers. The cigarettes were administered under double-blind conditions during three visits to the laboratory separated by a minimum of 1 week. Marijuana smoking, but not placebo smoking, was associated with significant depersonalization that was maximal 30 min after smoking the high-potency cigarettes. Other behavioral changes induced by marijuana included disintegration of time sense, sensation of "high," increased state anxiety, tension, anger, and confusion. Respiration, pulse rate, and systolic blood pressure also increased after marijuana smoking. Multiple regression identified temporal disintegration as the most significant predictor of depersonalization.
Duke Scholars
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Related Subject Headings
- Substance-Related Disorders
- Respiration
- Regional Blood Flow
- Psychiatry
- Marijuana Smoking
- Male
- Humans
- Heart Rate
- Double-Blind Method
- Depersonalization
Citation
Published In
DOI
ISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Substance-Related Disorders
- Respiration
- Regional Blood Flow
- Psychiatry
- Marijuana Smoking
- Male
- Humans
- Heart Rate
- Double-Blind Method
- Depersonalization