Changes in cerebral blood velocity after intravenous diazepam.
Publication
, Journal Article
Mathew, RJ; Wilson, WH; Humphreys, DF; Lowe, JV; Wiethe, KE
Published in: Biol Psychiatry
April 1, 1992
Cerebral blood velocity (CBV) was measured with transcranial Doppler in 6 normal right-handed male volunteers before and for 50 min after an intravenous injection of 0.1 mg/kg of diazepam and normal saline during 2 separate visits to the laboratory. Blood pressure, pulse rate, end tidal levels of carbon dioxide and mood changes were quantified before and after the injections. Diazepam injection was associated with significant increases in fatigue and sleepiness. There were no significant changes in end tidal carbon dioxide, respiration, pulse rate, and blood pressure after the injection. Postdiazepam CBV was significantly lower following diazepam compared to CBV following placebo.
Duke Scholars
Published In
Biol Psychiatry
DOI
ISSN
0006-3223
Publication Date
April 1, 1992
Volume
31
Issue
7
Start / End Page
690 / 697
Location
United States
Related Subject Headings
- Psychiatry
- Personality Inventory
- Male
- Injections, Intravenous
- Humans
- Echoencephalography
- Double-Blind Method
- Diazepam
- Brain
- Blood Flow Velocity
Citation
APA
Chicago
ICMJE
MLA
NLM
Mathew, R. J., Wilson, W. H., Humphreys, D. F., Lowe, J. V., & Wiethe, K. E. (1992). Changes in cerebral blood velocity after intravenous diazepam. Biol Psychiatry, 31(7), 690–697. https://doi.org/10.1016/0006-3223(92)90278-8
Mathew, R. J., W. H. Wilson, D. F. Humphreys, J. V. Lowe, and K. E. Wiethe. “Changes in cerebral blood velocity after intravenous diazepam.” Biol Psychiatry 31, no. 7 (April 1, 1992): 690–97. https://doi.org/10.1016/0006-3223(92)90278-8.
Mathew RJ, Wilson WH, Humphreys DF, Lowe JV, Wiethe KE. Changes in cerebral blood velocity after intravenous diazepam. Biol Psychiatry. 1992 Apr 1;31(7):690–7.
Mathew, R. J., et al. “Changes in cerebral blood velocity after intravenous diazepam.” Biol Psychiatry, vol. 31, no. 7, Apr. 1992, pp. 690–97. Pubmed, doi:10.1016/0006-3223(92)90278-8.
Mathew RJ, Wilson WH, Humphreys DF, Lowe JV, Wiethe KE. Changes in cerebral blood velocity after intravenous diazepam. Biol Psychiatry. 1992 Apr 1;31(7):690–697.
Published In
Biol Psychiatry
DOI
ISSN
0006-3223
Publication Date
April 1, 1992
Volume
31
Issue
7
Start / End Page
690 / 697
Location
United States
Related Subject Headings
- Psychiatry
- Personality Inventory
- Male
- Injections, Intravenous
- Humans
- Echoencephalography
- Double-Blind Method
- Diazepam
- Brain
- Blood Flow Velocity